Chapter 5 - Integumentary System Flashcards
What makes up the integumentary system?
Skin, hair, nails, and cutaneous glands
What percentage of body weight does your skin make up?
7-15%
What tissue types make up the integumentary system?
All 4
What are the two primary regions of the skin? What is the region that is not part of the skin but often studied together?
- epidermis
- dermis
Not skin - hypodermis
What does the skin protect against?
Resists physical trauma and infection (keratin and desmosomes)
Bacterial invasion (sebum is acidic, dendritic cells phagocytize pathogens, outer layer is dead and dry)
UV Radiation
How does the skin regulate water loss/absorption?
Keratinized cells control water entering/leaving the body
Insensible and sensible perspiration
What is the difference between insensible and sensible perspiration?
Insensible is the release of water when not visibly sweating, sensible is visible sweat
Why is the skin important in vitamin D production?
Vitamin D production is important in bone development and requires small amounts of UV light to produce
How does the skin gather sensory information?
It’s the largest sensory organ. It senses tough, pressure, pain, and temperature and supply the CNS with information about external condictions
How does the skin regulate body temperature?
Thermoreceptors
When body temp increases, blood vessels dilate and sweat glands become active
When body temp decreased, blood vessels constrict and piloerector muscles contract
How does the skin help with communication?
Facial expression
What are the 5 layers of the epidermis?
(starting at outermost layer)
- Stratum corneum
- Stratum lucidum
- Stratum granulosum
- Status spinosum
- Stratum basale
Which of the 5 layers of the epidermis is only found in thick skin?
Stratum lucidum
What type of epithelium makes up the epidermis?
Keratinized stratified squamous epithelium
Describe the epidermis (types of cells, vascular/avascular, nerves, etc)
Outer, thin region
Dead cells
Lacks blood vessels - diffusion of nutrients comes from basement membrane/CT
Few nerve endings - touch and pain
What types of cells make up the epidermis?
- stem cells
- keratinocytes
- melanocytes
- tactile (merkel)
- dendritic cells
What are epidermal stem cells are where are they found?
Undifferentiated cells
Found int he stratum basale
What do keratinocytes do?
Synthesize keratin (most of the epidermal cells)
What do melanocytes do and where are they found?
Synthesize the pigment melanin (which shields DNA)
Found in the statue basale
What do tactical/merkel cells do and where are they found?
Touch receptor cells associated with dermal nerve fibers
Found in the stratum basale
What do dendritic cells do and where are they found?
Act as macrophages/immune cells
They originate in bone marrow
Found in the stratum spinosium and stratum granulosium
What happens in the stratum basle?
Constant cell division
What happens in the stratum spinosum
Some cell division, keratin produced
Cells flatten superficially
What happens in the stratum granulosum?
lamellar bodies release lipid contents
Cornified cellular envelope develops (CE)