Chapter 5 ( Fertilisation and organogenesis) Flashcards
Function of fertilization
- provides for the recombination of paternal and maternal genes, thus restoring the original diploid number of chromosomes
- activates the eggs to begin development.
What is fertilization
This is the union of male and female gametes to form a zygote.
spermatozoa come into contact with the eggs by
random movement.
What happens when the head of a spermatozoon hits the vitelline membrane
the acrosome at the tip of the head bursts open, releasing a substance (sperm lysin) which softens the vitelline membrane at the point of contact.
What’s capacitation
This is an activating process involving the removal of a layer of glycoprotein and plasma proteins from the outer surface of the sperm.
Capacitation takes how many hours?
7hrs
membrane becomes more permeable to Ca** which have the dual effects of?
increasing the beating activity of the sperm tail and promoting the acrosome reaction.
What’s acrosome reaction?
acrosome membrane fuses with the cell membrane, which starts the release of acrosomal enzymes which pierce the egg membranes.
What enables the spermatozoon to penetrate into the cytoplasm of the egg?
Acrosome reaction
Further sperms are prevented from entering the ovum by
cortical reaction
What is cortical reaction?
cortical granules migrating through the plasma membrane and applying themselves to the inner surface of the vitelline membrane fluid which cause the thickening of the vitelline membrane
What is fertilization membrane?
Thickened vitelline which appears to lift off from the egg surface
How is the nucleus of the sperm and ovum fuse ?
Commonly the nuclear membranes break down, a spindle is formed, and the now visible sperm and egg chromosomes arrange themselves on the spindles as in mitosis.
Development of zygotes starts with
cleavage,
What is cleavage ?
zygote dividing repeatedly by mitosis into progressively smaller cells or blastomere.
List and explain the different yolk distribution
- Homolecithal or isolecithal: Even distribution of yolk
- Telolecithal: yolk is concentrated towards one pole known as the vegetal pole
- centrolecithal: The amount of yolk is large, and it is collected compactly in the centre of the egg cell.
- Discoidal eggs: The amount of yolk is so enormous that the non-yolky part of the cell forms a mere microscopic spot, or blastodisk, on top of the yolk mass