chapter 5 and 6 flashcards

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1
Q

How many net ATPs are produced when prokaryotic cell oxidizes 1 glucose ?

A

32 ATP

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2
Q

how many net ATPs are made when eukaryotic cell oxidizes 1 glucose ? Why?

A

30 ATP (use 2 ATP to bring glucose into mitochondria) for eukaryotes

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3
Q

In cellular respiration, what Is the final electron acceptor if oxygen is not available?

A

pyruvate

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4
Q

Which intermediate in glycolysis is not a shared one in gluconeogenesis ?

A

Oxaloacetate (only in gluconeogenesis)

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5
Q

What are nucleophiles ?

A

nucleophiles are the species that use their electrons to attack other atoms and attach themselves to the atoms.

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6
Q

how is glucose used in muscle ?

A

glucose used as a Quick source of energy through ATP production

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7
Q

What are non-reducing sugars ?

A

. Non-reducing residues within sugars are those that do not have an OH at the anomeric carbon,

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8
Q

Where does gluconeogenesis occur?

A

Liver

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9
Q

What happens if glycogen cannot breakdown ?

A

if no glycogen breakdown occurs, no glucose is available to enter glycolysis

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10
Q

What happens to intracellular calcium during muscle contraction ?

A

intracellular calcium rises during muscular contraction

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11
Q

What activates glycogen phosphorylase?

A

glycogen phosphorylase activated by:
-muscular contraction (increased intracellular calcium)
-phosphorylation

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12
Q

what is glycogen phosphorylase used for ?

A

Glycogen breakdown

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13
Q

Can muscle release glucose into the bloodstream ?

A

No, because muscle lacks the enzyme glucose-6-phosphatase it is unable to convert glucose-6-P (produced during muscle glycogen breakdown) to uncharged glucose capable of crossing the muscle cell membrane. Thus muscle cannot release glucose to the bloodstream

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14
Q

Where is glycogen stored?

A

LIVER

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15
Q

where is fat stored?

A

Adipose tissue

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16
Q

What occurs in reciprocal regulation ?

A

Reciprocal regulation prevents futile cycles (glycogen synthesis and degradation) from running simultaneously

17
Q

Where does glycolysis occur ? Does it require oxygen? What is electron carrier ?

A

Glycolysis occurs in CYTOSOL
-NO it does not require oxygen
-NAD

18
Q

Why is PFK (phosphofructokinase) considered committed step ?

A

PFK commits the sugar fructose 1, 6 bisphosphate to glycolysis

19
Q

What are the three enzymes that are part of committed steps in glycolysis ?

A
  1. Hexokinase
  2. PFK (phosphofructokinase)
  3. Pyruvate kinase (last step of glycolysis)
20
Q

What occurs in the process of fermentation ?

A

Fermentation is the process by which NADH is oxidized to NAD+ under anaerobic conditions.
This reaction occurs with the generation of lactate from pyruvate and allows glycolysis to proceed in the absence of oxygen

21
Q

What occurs in Krebs cycle?

A

The Krebs cycle oxidizes the two carbon equivalents of acetyl-CoA.
The carbon atoms that are oxidized to carbon dioxide in the Krebs cycle do not directly come from acetyl-CoA, but rather come from oxaloacetate (OAA)

22
Q

How is Krebs cycle coupled to ETC (electron transport chain )?

A

Electron carriers from Krebs cycle are reduced.
Then the electron carriers from krebs are OXIDIZED in ETC

23
Q

Which forms of energy do Krebs cycle produce

A

Krebs proudces energy in forms of NADH (3) and FADH2 (1)

24
Q

What are structural isomers? Example ?

A

Structural isomers: two molecules with Different connectivity
example D glucose (aldose) and D fructose (ketone)

25
Q

What are epimers?

A

epimers differ in configuration at a SINGLE chiral center

26
Q

What are diastereomers ?

A

Diastereomers have opposite configuration at some but not all chiral centers

27
Q

What are enantiomers ?

A

sugars that are mirror images if each other , and have opposite absolute configurations at all chiral centers

28
Q

which forms do glucose predominantly exist?

A

glucose predominantly exists as:
-hexose
-aldose
-pyranose