Chapter 5 Flashcards
a hormone that aids absorption of dietary calcium and phosphorus
calcitriol (from vitamin d)
cutaneous membrane, covers about 2 square meters of body, 7 percent of total body weight
skin
flexion creases
areas of attachment to the finger joints or the toe joints
layer of skin that consists of loose connective tissue with collagen and elastic fibers; contains fibroblasts, adipocytes and macrophages - stores half of the bodies fat
subcutaneous layer/hypodermis
Which epidermal layer includes stem cells that continually undergo cell division?
stratum basale
is a yellow-red or brown-black pigment that contributes to skin color and absorbs damaging ultraviolet (UV) light.
melanin
develop from ectoderm of a developing embryo and produce pigment melanin
melanocytes
hardening process of keratin and cells arise from basal layer to surface requires 4-6 weeks
kerartinization
psoriasis
chronic disease, sloughing occurs in 1 week instead 4-6 weeks for keratinocytes to reach the surface
the thickest layer in thick skin and can get thicker due to mechanical stress (epidermal layer)
stratum corneum
How are epidermal ridges formed? How are surface grooves formed?
- from interpapillary pegs penetrated by sweat glands
- from interpapillary pegs NOT penetrated by sweat glands
three pigments of the skin and their contribution to the skin colour
1) eumelanin = brown or black pigment
2) pheomelanin = yellow-red pigment
3) carotene = yellow orange pigment (for vision)
- abnormal thickening of stratum corneum caused by chronic fiction
- constant exposure of skin to friction causes?
- callus
- increased cell production and keratin production
tyrosinase
used ofr melanin synthesis to make melanosomes (melanin granules)
difference between dark-skinned and light-skinned
- variations in skin colour due mainly to amount and types of melanin and their distributions
- large amounts of melanin in epidermis = dark
- opposite = light
pale skinned people are often _____because of their lack of melanin means color of blood in dermal capillaries shows through
vascular
poor protection from UV light
sun tanning
- increased melanin in skin
- melanin protect keratinocytes from possible UV-induced chromosal change
patchy accumulations of melanin in skin, fade in winter
skin freckles
patchy accumulations of lipofuscin-filled basal epithelial cells
age spots
genetic defect, inability to produce melanin in skin, hair and eyes, absence of tyrosinase, skin burn easily due to overexposure to sunlight
albinism (albinos are affected)
skin disorder, partial or complete loss of melanocytes from areas of skin (micheal jackson), autoimmunity that antibodies attack and kill melanocytes
virtiligo
melanocytic nevi
moles, skin growths from accumulations of melanocytes
dendtric cells from bone marrow, involved in immune mechanisms, antigen-presenting cells (APCs) help t-lymphocutes kill microbed
intraepidermal macrophages (non-keratinocytes in epidermis)
in stratum basale of hairless skin, detect some touch stimuli, synapses with a tactile disc (merkel disc)( at end of a sensory neuron
tactile epithelial cells (merkel cells) (non-keratinocytes in epidermis)
layer of skin where collagen fibers are most abundant with some elastic and reticular fibers - divides into 2 layers
Dermis
areolar connective tissue, dermal papillae, superficial layer
papillary region
what can be found in the dermal papillae
touch corpuscles (Meissner corpuscles) , free nerve endings (action potentials), capillary loops (blood vessels)
dense irregular connective tissue containing collagen, reticular and elastic fibers, makes tissue strong flexible extensible and elastic
reticular region