Chapter 5 Flashcards
Plasma Membrane
Separates its external environment from the outside world. Regulates passage of materials in and out of the cell; helps maintain homeostasis
Amphipathic Molecules
Contains two hydrophobic fatty acid chains linked to two of the three carbons of a glycerol is a negatively charged, hydrophilic phosphate group, linked to a polar, hydrophilic organic group
Phospholipids form bilayers of two distinct groups
One strongly hydrophobic and one strongly hydrophilic
Cylindrical Shape
Allow phospholipids to associate with water most easily as a bilayer
Amphipathic molecules with different shapes ten to form
Spherical structures in water
TEM of red blood cell
Hydrophilic heads of phospholipids are the parallel dark lines
Hydrophobic tails are the light zone between them
Phosopholipids bilayers behave like
Liquid crystals
Membrane fluidity depends on its
Component lipids
Biological membranes fuse and form
Closed vessicles
Can fuse with other bilayers, allowing vesicles to transfer materials from one compartment to another, or secrete a product from the cell
Biological Membranes
Integral Membrane Proteins
Amphipathic proteins firmly bound to the membrane
Transmembrane Proteins
Integral proteins that extend completely through the membrane
Peripheral Membrane Proteins
Located on inner or outer surface of plasma membranes, bound to exposed regions of integral proteins
A specific external domain of an instrinsic membrane protein is always found on the ____ of the membrane
Same side
Proteins associated with the membrane specialize for many essential activities
- Anchor the cell to its substrate
- Transport molecules across the membrane
- Catalyze enzymatic reactions near the cell surface
- Receive information from other cells in the form of chemical or electrical signals
- Serve as a identification tag
By regulating chemical traffic across its plasma membrane, a cell controls its
Volume and its internal ionic and molecular composition
Biological membranes are most permeable to
Small nonpolar molecules
The lipid bilayer is relatively impermeable to
Charged ions and most large polar molecules
Transport Porteins
Move ions, amino acids, sugars and other needed polar molecules through membranes
Two main types of transport proteins
Carrier and Channel
Bind the ion or molecules and change shape, moving the molecule across the membrane
Carrier Protein Transporters
Transfer of solutes by carrier proteins located within the membrane
Carrier Mediated Transport
ABC Transporters
Use energy donated by ATP to transport certain ions, sugars and polypeptides
Channel Proteins
Forms pores in membrane. Cells regualte passage of materilas through the channels. Channels transport water and specific types of ions.