Chapter 45.1 Flashcards
Overview
Hormones
chemical signals that are secreted into the circulatory system and communicate regulatory messages within the body
Two systems coordinate communication throughout the body:
Endocrine System
The endocrine system secretes hormones that coordinate slower but longer-acting responses including reproduction, development, energy metabolism, growth, and behavior
Slow & long-lasting
Two systems coordinate communication throughout the body:
Nervous System
The nervous system conveys high-speed electrical signals along specialized cells called neurons; these signals regulate other cells
Fast & Short-lasting
Local Regulators
Local regulators are molecules that act over short distances, reaching target cells solely by diffusion
Paracrine Signaling
In paracrine signaling, the target cells lie near the secreting cells
Autocrine Signaling
In autocrine signaling, the target cell is also the secreting cell
Pheromones
- Members of the same animal species sometimes communicate with pheromones, chemicals that are released into the environment
Endocrine Tissues and Organs
Endocrine Glands
- In some tissues, endocrine cells are grouped together in ductless organs called endocrine glands
- Endocrine glands secrete hormones directly into surrounding fluid
Endocrine Tissues and Organs
Exocrine Glands
Have ducts and which secrete substances onto body surfaces or into cavities
opposite of endocrine glands
Signal Transduction
The process by which a cell responds to substances outside the cell through signaling molecules found on the surface of and inside the cell.
Epinephrine
- The hormone epinephrine has multiple effects in mediating the body’s response to short-term stress
- Epinephrine binds to receptors on the plasma membrane of liver cells
- This triggers the release of messenger molecules that activate enzymes and result in the release of glucose into the bloodstream
Signaling by Local Regulators
- Local regulators are secreted molecules that link neighboring cells or directly regulate the secreting cell
- Types of local regulators:
- Cytokines and growth factors
- Nitric oxide (NO)
- Prostaglandins
Prostaglandins
- In the immune system, prostaglandins promote fever and inflammation and intensify the sensation of pain
- Prostaglandins help regulate aggregation of platelets, an early step in formation of blood clots