Chapter 43 - The Nervous System Flashcards
All animals must be able to respond to ___________
Environmental Stimuli
- Detect stimulus (light, heat, touch)
- Ex. Photoreceptors, chemoreceptor
Sensory receptors
- Respond to sensory receptors
- Ex. Muscle, gland
Motor effectors
Consists of the brain and spinal cord
Central Nervous System
Consists of sensor and motor neurons
Peripheral Nervous System
Three types of neurons
- Sensory neurons
- Motor neurons
- Interneurons
Carry impulses to CNS
Sensory neruons
Carry impulses from CNS to effectors
Motor nuerons
- Provide more complex reflexes and associates functions
- Majority of neurons
- Learning and memory
Interneurons
Three parts of a nueron
- Cell body
- Dendrites
- Axon
Enlarged part of neuron containing the nucleus
Cell body
Short, cytoplasmic extensions that receive stimuli
Dendrites
Single, long extension that conducts impulses away from cell body
Axon
Supports neurons
Neuroglia
Multiple layers of cell membranes wrapped around axons
Myelin sheath
Two neuroglia in CNS
- White matter
2. Grey matter
Myelinated axons form _____?
White matter
Dendrites/cell bodies form ____ ?
Gray matter
Type of neuroglia in the PNS
Nerves
Myelinated axons are bundled to form ________
Nerves
A potential difference exists across every neuron’s plasma membrane
Membrane potential
Charge of cytoplasmic side?
Negative
Charge of extracellular fluid side?
Positive
Cytoplasm is negatively charged because of ____
Sodium -potassium pump
Brings two k+ into cell for every three Na+ pumped out
Sodium-potassium pump
- Moves away from poles (-70mv) and toward neutral (0mV)
- Because cytoplasm is negatively charged, ___________ makes the membrane potential more posotive
Depolarization
Voltage change makes it extremely negative (lower than -70mv)
Hyperpolarization
A change in membrane potential that moves down the axon
Action potentials
The cycle of action potentials
- From resting
- To depolarization
- To hyperpolarization
- Back to resting
Action potentials are proliferated by ________
Voltage-gated ion channels
What are the voltage-gated ion channels?
- Na+ channels
- K+ channels
_________ channels open first??
Na+ channels
What two things do Na+ open channels cause?
- An influx of Na+
2. Depolarization
_________ channels open second??
K+ channels
What two things do K+ channels cause?
- Cause the exist of K+
2. Hyperpolarization
When depolarization occurs, the change in charge is detected by __________
The adjacent Na+ channels
Once the cytoplasm is positive enough, it will cause ____
- The next channels to open
- Na+ to move in
- Depolarization to move down the axon
The positive point in action potential is known as _______
Threshold
___________ follows depolarization down the axon
Hyperpolarization
When hyperpolarization happens, what happens to the voltage gated ion channels?
- The K+ channels open after the Na+ ones do
2. This causes K+ to rush OUT
Comparative Chart for Na+ channels and K+ channels
Na+ Channels
- Open quickly
- Na+ flows into the cell
- Open first
- Depolarizes
K+ Channels
- Open slowly
- Na+ moves in
- K+ rushes out
- Hyperpolarizes
- Before an action potential
- -70mV
- Na+ moves downstream
- Contacts the voltage gated ion channel
- Raises the voltage
Resting potential
- First phase in action potential
- Enough Na+ can cause the voltage gated ion channel to open
- Na+ flows through the channel into the cell
- The region becomes depolarized
Rising action potential
- K+ voltage gated ion channels open next
- K + flows out of the cell
- Repolarizes cell to become negative
Falling action potential
- All the K+ causes the cell to become hyperpolarized
- Less negative than -70 mV
Undershoot
After the signal moves, that area of the axon becomes reset to the _________
Resting potential
How does resting potential happen?
Sodium Potassium Pump
The signal in action potential moves down the axon until it reaches the _________
Axon terminal
- Intercellular junctions between neurons
- The way action potential moves across
Synapses
Transmits action potential
Presynaptic Cell
Synapse that receives action potential
Postsynaptic Cell
Two types of synapses
- Electrical
2. Chemical
Vertebrates have mostly what kind of synapses?
Chemical
Chemical synapses have a _____________ , which is a space between the two cells
Synaptic cleft
End of presynaptic axon terminal in chemical synapses contain _________
Synaptic Vesicles
Synaptic vesicles are packed with _________
Neurotransmitters
The first four steps of Transmission
- Action potential moves down the axon
- Synaptic vesicles fuse with cell membranes
- Neurotransmitter is released into cleft
- Diffuses to other side of cleft
What causes the first graded potential on the postsynaptic cell?
Neurotransmitters activate ligand-gated ion channels on the postsynaptic cells
What are closed in the normal resting cell?
Ligand-gated ion channels
Induce openings of the ligand-gated ion channels
Neurotransmitters
What do neurotransmitters do after they activate Ligand-gated ion channels?
Cause changes in cell membrane permeability
The process of neurotransmitters in Transmission
- Bind to ligand-gated ion channels
- New action potential begins on the postsynaptic cell
- Neurotransmitter action is then terminated
What happens when the neurotransmitter action is then terminated?
- Enzymatic breakdown
- Cellular reuptake
- Allows for repition
Two ways to increase velocity of conduction
- Axon has a large diameter
2. Axon is myelinated
- Axon has less resistance to current flow
- Found primarily in invertebrates
When axon has a large diameter
- Spaces between myelin sheeth
- Action potential is only produced here
Nodes of Ranvier
Impulses jump from node to node
Saltatory conduction
When the axon is myelinated, what major thing does it contain?
Nodes of Ranvier
Prolonged exposure to a neurotransmitter may cause cells to love the ability to respond to it
Habituation
Example of habituation
Cocaine
How does cocaine have an effect on you?
- Affects the brains “pleasure pathways” (limbic system)
- Inhibits reuptake of neurotransmitter (stays in cleft)
- Cell decreases the number of receptors to reestablish homeostasis
- This results in decreased neuron activity in normal conditions
________ are the only major phylum without nerves
Sponges
_________ have the simplest nervous system
Cnidarians
- Cnidarians
- Neurons linked to each other in a ________
Nerve net
What group has NO association to neurons and one big reflex machine?
Cnidarians
_________ are the simplest animals with associative activity
Free-living Platyhelminthes
Three components of Free-living Platyhelminthes nervous sytem
- Two nerve cords run down the body
- Permit complex muscle control
- Rudimentary “brain”
All other nervous systems in other invertebrates are basically elaboration on the ________ model
Platyhelminth
__________ have a CNS that connect to the periphery
Earthworms
________ have a coordination centers in the front, and branching nerve chords
Arthropods
__________ have several giant axons connecting to relatively large-sized brain
Cephalopods
Why are the vertebrate brains different than other brains?
An enlargement of the anterior portion of the nerve cord
Three basic divisions of the vertebrate brain
- Hindbrain
- Midbrain
- Forebrain
Part of the brain that processes blood flow
Hindbrain
Part of the brain that processes visual information
Midbrain
Part of the brain processes olfactory information
Forebrain
What part of the brain has evolved in vertebrates and become the dominant feature
Forebrain
The increase in brain size in mammals reflects the great enlargement of the ________
Cerebrum
The cerebrum is split into right and left _____, which are connected by a tract called the ________
- Cerebral hemisphere
2. Corpus callosum
Each hemisphere in the cerebrum __________ from the opposite side
Receives sensory input
Hemispheres are divided into what four lobes?
- Frontal
- Parietal
- Temporal
- Occipital
Part of the brain that integrates visual, auditory and somatosensory information
Thalamus
- Integrates visceral activities
- Controls pituitary gland
- Part of limbic system
Hypothalamus
The hypothalamus is apart of what system?
Limbic system
System responsible for emotional response
Limbic system
A cable of neurons extending from the brain down through the backbone
Spinal cord
The spinal cord in enclosed and protected by the ________ and ___________
- Vertebral column
2. Meninges
Membranes surrounding the spinal chord
Meninges
Two function of the spinal chord
- Serves as the body’s “information highway”
2. Reflexes
How does the spinal cord function as the body’s information highway?
- Functions to interpret simple information with interneurons
- Relays messages between the body and the brain
- The knee jerk is __________
Monosynaptic (no interneurons)
Most reflexes in vertebrates involves a ________
Single neuron
What does the peripheral nervous system consist of?
- Nerves
2. Ganglia
Bundles of axons bound by connective tissue
Nerves
Aggregates of neuron cell bodies
Ganglia
____________ stimulate the skeletal muscles to contract
Somatic Motor Neurons
What are somatic motor neurons in response to?
Conscious command or reflex actions
How many neurons do the somatic motor neurons need?
One motor neuron
Subconscious control
The Autonomic Nervous System
Motor pathway of the autonomic nervous system has how many motor neurons
Two
What is the process of autonomic nervous system?
- The first neuron exits the CNS and synapses at autonomic ganglia
- The second exist the ganglion and regulates effectors (smooth or cardiac muscle or glands)
Five facts about Sympathetic Division
- FIght or flight
- Heightened metabolism
- Reduce digestion
- Increase alertness
- Increase respiration
Four facts about Parasympathetic Division
- Slow heart rate and breathing
- Increase digestive functions
- Relaxed state