Chapter 4: Hyaline Cartilage (Exam 2) Flashcards
Interstitial cartilage growth begins with what?
A grouping of rounded mesenchymal cells that can be called chondrogenic nodules
chondrificaton within chondrogenic nodules involves what?
mesenchyme cells differentiate into chondroblasts
What are two important factors affecting the differentiation of mesenchyme cells into chondroblasts?
- transcription factor being expressed (SOX-9)
2. forces exerted in the area
during interstitial cartilage growth chondroblasts will secrete what?
will secrete matrix components when they are activated
Matrix concentrates/sets up and chondroblasts do what?
they mature (differentiate) into chondrocytes once enough matrix has surrounded them
What are two things chondrocytes will likely do?
- secrete matrix -> territorial matrix
2. divide if they have enough energy leading to isogenic groups
cartilage development expands in what direction?
outward
what is the stopping point of cartilage development?
chondrogenic perichondrium
what does fibrous perichondrium develop from?
surrounding vascular mesenchyme tissue
what is the cartilage growth mechanism?
a modified version of interstitial growth
Where is interstitial growth found?
- articular cartilage
2. epiphyseal growth plates
Is appositional cart growth faster or slower than interstitial?
appositional growth is much slower
which type of cartilage growth, appositional or interstitial, more common?
appositional growth is more common
appositional cartilage growth happened in whom?
fetuses, chidden regularly, and as a form of healing in adults
the process of appositional growth originates within what layer?
the perichondrium
chondrogenic cells and chondroblasts become what in appositional cartilage growth?
they become active
how is it that chondrogenic cells become chondrocytes?
they differentiate into chondroblasts and secrete matrix all around themselves which will cause then to differentiate again into chondrocytes
In appositional growth new chondroblasts can also develop from what?
fibroblasts in the fibrous perichondrium
In appositional growth new chondrogenic perichondrium develops from what?
the previous fibrous perichondrium (all shifting outward)
New fibrous perichondrium develops from what in appositional growth?
the surrounding CT
Appositional growth functions to do what?
enlarge existing cartilage and in healing (which doesn’t heal very well)
