Chapter 4: Cartilage (exam 2) Flashcards
Cartilage is a what type of CT?
Specialized type of CT
Cartilage is semi-rigid yet…
flexible
Cartilage cells and matrix immediately surrounding these cells have no what?
no capillary networks of their own
How is nutrition brought to the cartilage?
Diffusion (the thicker the cartilage the harder it is to diffuse)
what are the functions of cartilage (2)
Support and act as a template for endochondral bone ossification
What are the three types of cartilage?
Hyaline (MC), elastic and fibrocartilage
Elastic cartilage is a specialized type of what?
hyaline cartilage
Fiber type in Hyaline (H), Elastic (E) and Fibrocartilage (F)
H- Collagen II. E-Collagen II and Elastic.
F- Collagen I
Does hyaline, elastic, and/or fibrocartilage have a perichondrium?
H- yes, usually
E- yes, always
F- No
Places that hyaline cartilage is found?
Most of the larynx, tracheal rings + bronchi, articular cart, thyroid, nasal septum, costal cartilage
Places that Elastic cartilage is found?
Cartilage in the larynx, ear pinna, external auditory tube, epiglottis
Places that fibrocartilage is found?
Annular fibrosis of IVD, knee menisci, pubic symphisis, insertion of some tendons
Hyaline cartilage matrix is made up of what?
Ground Substance and Fibers
What is hyaline cartilage matrix made up of?
Aggrecans, hyaluronic acid, proteoglycans and chondronectin
Aggrecans found in the ground substance is what?
Large molecules composed of Protein (form the core) and Sulfated GAG’s (100-200/aggrecans)
Some examples of sulfated GAG’s?
chondroitin sulfate, keratin sulfate, heparin sulfate
Hyaluronic acid is also known as what?
Hyaluronan
Each hyaluronic acid bonds to what?
Many aggrecans
what is held between HA and the aggrecans?
large amounts of water
Other proteoglycans found in the matrix of hyaline cartilage does what?
It does not form aggregates, binds to other molecules, and helps stabilize matrix
Chondronectin is a what?
is an adhesive glycoprotein
Fibers in the matrix of hyaline cartilage are what?
primarily Collagen II and some Collagen IX, X, XI