Chap 5: Bone (clinical aspect) (exam 2) Flashcards

1
Q

Somatotropin influences what

A

Bone growth

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2
Q

Somatotropin increases the numbers of what cells?

A

osteoblasts and fibroblasts

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3
Q

If somatotropin is low, what happens to bone density

A

it will be low

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4
Q

What is scurvy caused by?

A

a vit. C deficiency

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5
Q

Scurvy affects what?

A

Collagen I fibers

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6
Q

Scurvy reduces what?

A

bony matrix and bone development

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7
Q

Scurvy delays what process

A

bone healing

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8
Q

Rickets is caused by what?

A

a vitamin D deficiency

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9
Q

Osteomalacia is caused by what?

A

a prolonged vitamin D deficiency in adults

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10
Q

in Osteomalacia newly formed bone doesn’t what?

A

does not ossify properly which forms weak bones

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11
Q

Osteoporosis primarily effects what cells?

A

osteoblasts and osteoclasts

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12
Q

what are three signs of osteoporosis?

A
  1. curvature of the spine
  2. severe back pain
  3. decreases in height
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13
Q

what are the two types of osteoporosis

A
  1. postmenopausal

2. age-related

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14
Q

Postmenopausal osteoporosis effects women over what age?

A

50

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15
Q

Postmenopausal osteoporosis is caused by what?

A

decreased estrogen levels

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16
Q

Does age-related osteoporosis affect women or men more frequently?

A

affects the both of them

17
Q

Age-related osteoporosis is due to low levels of what?

A

Somatotropin (HGH)

18
Q

estrogen reduces the life span of what cell while increases the lifespan of what cell?

A

Decreases osteoclast lifespan

increases osteoblast lifespan

19
Q

estrogen stimulates osteoblasts to secrete what?

A

osteoid

20
Q

estrogen slows bone what?

A

bone remodeling

21
Q

If there is decreased estrogen, what is believed?

A

osteoclasts dig deeper resorption cavities that osteoblasts can’t fill

22
Q

Estrogen replacement protected women from fracture but this is eliminated in women who do what?

A

smoke

23
Q

Smokers have less effective absorption of what?

A

calcium

24
Q

Smokers tend to have an earlier what than nonsmokers?

A

earlier menopause

25
Q

The relationship between smoking and osteoporosis is very clear. T/F

A

False it is unclear

26
Q

what are some factors leading to osteoporosis?

A
long use of glucocorticoids
antacid use w/Al
high protein diet
excessive thyroid use
anticonvulsant
27
Q

what are three steps to prevent Osteoporosis

A
  1. Balanced diet
  2. weight bearing exercise
  3. healthy life choices