Chapter 3.6 (page 66)

Question 1

Identify the three types of parenchymal cells (involved in healing).

Answer 1

Labile

Stable

Permanent

Question 2

Healing involves either _________ or _____________, and uses similar physiologic pathways.

Answer 2

Regeneration

Fibrosis [Replacement]

Question 3

_____________ involves replacement of the injured tissue with cells of the same type.

Answer 3

Regeneration

Question 4

Regeneration can only occur in cells able to undergo __________.

Answer 4

Mitosis

Question 5

Healing emanates from ________________.

Answer 5

Parenchymal Cells

Question 6

This repair process occurs by replacement of damaged cells with connective tissue, a process that involves generation of ________ and ____________.

Answer 6

Scar tissue

Granulation tissue

Question 7

_____________: Cells that cannot undergo mitotic division. Once destroyed, they are replaced with fibrous scar tissue that lacks the functional characteristics of the destroyed tissue.

Answer 7

Permanent Cells

Question 8

These are cells that normally stop dividing when growth ceases, however, they are capable of undergoing
regeneration when confronted with an appropriate stimulus.

Answer 8

Stable Cells

Question 9

____________: Cells that continue to divide and replicate throughout life.

Answer 9

Labile Cells

Question 10

Give 2 examples of each type of parenchymal cells.

Answer 10

Labile Cells

• Skin
• Gastrointestinal Tract

Stable Cells

• Liver cells
• Smooth muscle cells

Permanent Cells

• Nerve Cells
• Cardiac Cells

Question 11

Granulation tissue grows into a wound from nearby connective tissue within the few days after healing begins [_________].

Answer 11

3-4 days

Question 12

Granulation tissue is much more extensive in wounds that heal by ____________ [large wounds]. It is created by fibroblasts and vascular endothelial cells that are drawn to the area by chemotaxis from macrophages in the wound.

Answer 12

Second Intention

Question 13

Granulation tissue appears to be moist and pinkish or reddish in colour because it is _______________.

Answer 13

Highly vascular

Question 14

Scar tissue is made up of connective tissue and is also called _________.

Answer 14

Fibrosis

Question 15

____________ from fibroblasts make up the tissue and as they mature, they link together and shorten, creating a tight, strong scar.

Answer 15

Collagen Proteins

Question 16

The supportive framework of an organ (or gland or other structure), usually composed of connective tissue.

Answer 16

Stroma

Question 17

The stroma of the thyroid gland is the ______________________ of the thyroid gland.

Answer 17

Connective tissue that supports the lobules and follicles

Question 18

The key elements of an organ essential to its functioning, as distinct from the capsule that encompasses it and other supporting structures.

Answer 18

Parenchyme

Question 19

The parenchyma is opposed to the ________ of an organ.

Answer 19

Stroma

Question 20

The parenchyma of the testis consists of what are called the _______________.

Answer 20

Seminiferous tubules

Question 21

Identify 5 local factors that can modify healing.

Answer 21

• *1. Blood flow
  2. Infection
  3. Presence of foreign particles
  4. Mobility of area
  5. Location of injury**

Question 22

Identify 4 systemic factors that can modify healing.

Answer 22

• *1. Age
  2. Nutrition
  3. Bleeding abnormalities
  4. Illness**

Question 23

Identify 3 factors that can modify healing relative to an agent used.

Answer 23

1. Dose

2. Potency

3. Route of Entry