Chapter 3.3 (page 56) Flashcards
The 3 Basic Stages of Acute Inflammation are:
- *1. Vasodilation & Increased Permeability of Blood Vessels
2. Phagocyte Migration from Blood to Interstitial Fluid
3. Tissue Repair**
Identify the traditional latin names for the 5 cardinal signs of an acute inflammatory response.
Rubor
Calor
Dolor
Tumor
Functio Laesa
This phase leads to an increase in blood flow and changes to the small blood vessels of the microcirculation. (Acute inflammation)
The Acute Vascular Phase of Inflammation
The Acute Vascular Phase of Inflammation
For a minor injury, ___________ is over in a few seconds but it is longer if the injury is more serious.
Vasoconstriction
The Acute Vascular Phase of Inflammation
A period of _____________ follows vasoconstriction. _________ involves arterioles and venules with a resultant increase in capillary blood flow.
Capillary Vasodilation
Vasodilation
The Acute Vascular Phase of Inflammation
The dilated vessels are also more permeable to fluid and cells and so protein-rich fluid or ________ pours into the extra-vascular spaces.
Exudate
The Acute Vascular Phase of Inflammation
What are the 3 common types of Chemical Mediators?
Histamine
Kinins
Arachidonic Acid Metabolites
The Acute Vascular Phase of Inflammation
Kinins: Protein-based substance; Formed in blood from precursors called _________.
**Kininogens **
The Acute Vascular Phase of Inflammation
_______________: This is a chemical mediator found in phospholipids of cell membranes (unsaturated fatty acid). This is released by enzymatic action of _____________.
Arachidonic acid metabolite
Basophils and Mast cells
The Acute Vascular Phase of Inflammation
Arachidonic Acid metabolites lead to creation of ___________ and ___________.
Prostaglandins
Leukotrienes
The Acute Vascular Phase of Inflammation
This mediator induces vasodilation and affect nerve endings and cause pain.
Kinins
The Acute Vascular Phase of Inflammation
Arachidonic Acid Metabolites play a role in ___________ and _____________.
Asthma
**Anaphylaxis **
The Acute Vascular Phase of Inflammation
Which of the common types of chemical mediators aid in blood clotting?
Arachidonic Acid Metabolites
The Acute Vascular Phase of Inflammation
Found in many body cells but are highest in Mast cells, Basophils, and Platelets.
Histamine