Chapter 3.4: Acyclic Molecules with Two or More Stereocenters

Question 1

In the R,S system R,R and S,S are?

Answer 1

enantiomers

Question 2

What is an achiral compound possessing two or more chiral centers that also has chiral isomers?

Answer 2

meso compound

Question 3

What RS combos are enantiomers in the R,S system?

Answer 3

R,R and S,S

R,S and S,R

Question 4

When will the molecules be meso compounds according to the R,S system?

Answer 4

 Will be the R,S = S,R stereoisomer if both chiral centers have the same 4 groups attached

Question 5

What is a 2-D representation of a molecule; in these projections, groups on the right and left are by convention in front, while those at the top and bottom are to the rear?

Answer 5

fischer projections

Question 6

What  Will be the R,S = S,R stereoisomer if both chiral centers have the same 4 groups attached?

Answer 6

meso compound

Question 7

Define Meso compound

Answer 7

an achiral compound possessing two or more chiral centers that also has chiral isomers

Question 8

Define fischer projections

Answer 8

a 2-D representation of a molecule; in these projections, groups on the right and left are by convention in front, while those at the top and bottom are to the rear

Question 9

In the R,S system R,R and S,R are?

Answer 9

enantiomers

Question 10

How does R,S system adjust when H is in front?

Answer 10

• If molecule has H in front –> reverse what you have
o Clockwise = S
o Counterclockwise = R

Question 11

What is the relationship between stereoisomers and chiral centers?

Answer 11

• When two or more stereocenters exist in a molecule, multiple stereoisomers are possible for a molecule with n chiral centers, the max number of stereoisomers possible is 2^n