Chapter 3 Part 2 lecture Flashcards

1
Q

Meitosis is cell division. Cell devision is:

A

is a process by which cells reproduce themselves

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2
Q

3 interphase components:

A
  • G1 phase
  • S phase
  • G2 phase
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3
Q

4 mitotic phase components:

A
  • Prophase
  • metaphase
  • anaphase
  • telophase
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4
Q

PMAT AKA

A

Mitotic phases

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5
Q

4 components of G1 phase:

A
  • takes 8-10 hours
  • cell metabolically active
  • duplicates organelles and cytosolic components
  • centrosome replication begins
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6
Q

2 components of S phase

A
  • takes 8 hours

- DNA replicated

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7
Q

4 components of G2 phase:

A
  • Takes 4-6 hours
  • cell growth continues
  • enzymes and other proteins are synthesized
  • centrosome replication completed
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8
Q

Mitosis occurs when:

A

Mitosis occurs when the nucleus of a cell divides

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9
Q

Mitosis results in:

A

Mitosis results in the distribution of 2 sets of chromosomes into 2 separate nuclei

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10
Q

Mitosis is divided into ____ steps:

A
  • Prophase
  • Metaphase
  • Anaphase
  • Telophase
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11
Q

During prophase what happens with chromatin, chromosomes, chromatids and centromeres??

A

During prophase, Chromatin wrap around histone proteins and condenses into chromosomes; which are two sister chromatids joined at centromere

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12
Q

What are chromatins?

A

Stored form of DNA in our genes

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13
Q

3 steps of prophase:

A
  • chromatin condenses into chromosomes
  • nuclear membrane disappears
  • centrosomes move to opposite poles
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14
Q

1 step of metaphase:

A

-centromeres line up at metaphase plate

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15
Q

Metaphase plate AKA

A

Midline

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16
Q

What are kinetochores?

A

Kinetochores are a protein on the centrosome

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17
Q

How are mitotic spindles involved during metaphase?

A

mitotic spindles grab onto kinetochore proteins and pull them to line up on the metaphase plate

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18
Q

Chromosome histology appearance in early anaphase:

A

starting to split away from the metaphase plate/midline into sister chromatids

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19
Q

Chromosome histology appearance in late anaphase: (2)

A
  • sister chromatids are pulled apart and start moving toward centromere or polar ends
  • cleavage furrow
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20
Q

What is a cleavage furrow?

A

This furrow is the splitting of the cell itself

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21
Q

What is the cleavage furrow the start of?

A

it is the start of cytokinesis

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22
Q

Mitotic spindles AKA

A

Microtubles

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23
Q

steps of Telophase:

A
  • Mitotic spindles holding onto kinetochores dissolve
  • Chromosomes start to unravel into chromatins
  • New nuclear membrane forms
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24
Q

Nuclear membrane AKA

A

Nuclear envelope

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25
If mitosis is the splitting of the nucleus, cytokinesis is the
splitting of the cytoplasm or the cell
26
What happens after when cytokinesis is complete?
Interphase begins
27
What phase does cytokinesis start?
Anaphase
28
How does cytokinesis look in in the first step or anaphase?
-There's a slight cleavage furrow
29
How does cytokinesis/the cell look in the second step or telophase?
-Deeper cleavage furrow
30
How do the cells look in in the last step of cytokinesis or interphase?
- two identical cells to the original cells - chromatin - nuclear envelope - centrosomes
31
What are cells that remain in the G1 phase for a long time considered?
Considered to be in the G zero phase
32
What forms cleavage furrow?
Contractile ring
33
How many cell destinies are there?
3 cell destinies
34
What are the 3 cell destinies?
- Remain alive and functioning without dividing (G0 phase) - Grow and divide (meitosis) - Die (apoptosis or autolysis) single, family, dead
35
What does G0 do in the cell cycle?
G0 exits the cell cycle because it won't divide anymore
36
Apoptosis cell destiny is for:
programmed cell death
37
Autolysis cell destiny is for:
damage cell needing to be destroyed
38
DNA replication results in ___chromosomes and ___chromatids:
46 Chromosomes and 92 Chromatids
39
How are chromosomes counted?
By the number of centromeres
40
What does crossing over allow for?
It allows for differences in genetic coding
41
Gametes AKA
Sex cells
42
How many chromosomes are in the first step of prophase in meitosis?
46 Chromosomes
43
Lined up homologous pairs=
Tetrad
44
Tetrad are ___ sets of ____
tetrads are 4 sets of chromatids
45
Cells in meitosis telophase vs meiosis telophase
-in meitosis there are two identical cells formed while in meiosis, the four cells that are formed are different
46
How many chromosomes exist at the end of telophase 2 in meiosis?
23 chromosomes
47
How many chromatids are in prophase in meitosis?
96 chromatids because DNA is replicated
48
Prophase 1 in meiosis:
- Chromatins wind up to form chromosomes - nuclear envelope dissolved - Centrosomes go to opposite ends of cell - Mitotic spindles attach to kinetochores
49
Metaphase 1 in meiosis:
-mitotic spindles pull on kinetochore to line up homologous pairs along metaphase plate
50
Anaphase 1 in meiosis:
-pulling of homologous pairs to separate them
51
Telophase 1 in meiosis: (3)
- splitting of cell - development of nuclear envelope - dissolving of mitotic spindles
52
How many chromatids are in Prophase 2 in meiosis?
46 chromatids
53
After chromatids split in Anaphase 2 in meiosis, how many chromatids will there be?
23 chromatids
54
5 examples of genetic diversity:
- sperm cell - epithelial cell - red blood cell - nerve cell - smooth muscle cell
55
2 ways our cells deteriorate as we age:
- Our cells gradually deteriorate in their ability to function normally - and in their ability to respond to environmental stresses
56
How do the numbers of our cells change as we age?
The number of cells decrease as we age
57
How do our tissues deteriorate as we age?
We lose the integrity of the extracellular components of our tissues
58
Examples of deterioration as we age:
- Proteins may start to dissolve away | - Our bodies can't make as many cells
59
What are telomeres?
Telomeres are caps at the end of our DNA
60
What are telomeres for?
Used to protect DNA
61
How do telomeres deteriorate as we age? and how does that affect DNA?
-Degrade and come off and DNA starts to falter
62
5 types of cancer
- Melanoma - Sarcoma - Osteogenic sarcoma - leukemia - lymphoma
63
What is cancer and how do tumors form?
-growth and spread as signals to stop replicating is inhibited somehow
64
Causes of disorders such as cancer:
- environmental factors - genetic factors - bad habits like smoking, poor diet and exercise
65
Why is smoking terrible:
- nicotine and tar coats lungs - cause bacteria to form - genetic disorders occur in cells - cause rapid growth and lung cancer
66
How much intense exercise should be aimed for a week?
150 minutes a week
67
Treatments of cancer:
- early stages: cut it off | - spread through lymph: radiation