Chapter 3

Question 1

Sedative drug that, when used during pregnancy, can cause severe developmental damage to a fetus

Answer 1

Thalidomide

Question 2

Birth defect; impaired development of the arms, legs, or both

Answer 2

Phocomelia

Question 3

Physical sign, laboratory measurement, radiographic image, or other measure that is expressed to predict clinical benefit but it is not itself a measure of clinical benefit

Answer 3

Surrogate endpoint

Question 4

Measure of a therapeutic effect that is considered reasonably likely to predict the clinical benefit of a drug, such as an effect on irreversible morbidity and mortality

Answer 4

Intermediate clinical endpoint

Question 5

FDA policy allowing the change of suitable prescription drugs to over-the-counter status

Answer 5

Switching policy

Question 6

Drug-reduction policy aimed at reducing the supply of illegal drug and controlling other therapeutic drugs

Answer 6

Supply reduction

Question 7

Attempts to decrease individuals’ tendencies to use drugs, often aimed at youth, with emphasis on reformulating values and behaviors

Answer 7

Demand reduction

Question 8

Method of abuse prevention that protects drug users by teaching them responsibility

Answer 8

Inoculation

Question 9

Process that integrates substance abuse treatment, incentives, and sanctions and places nonviolent, drug-involved defendants in judicially supervised rehabilitation programs

Answer 9

Drug courts

Question 10

Policy of cutting off or destroying supplies of illicit drugs

Answer 10

Interdiction