Chapter 26 - PPP Flashcards
1
Q
The pentose phosphate pathway produces…
A
NADPH, ribose 5-phosphate, and provides an entry point for dietary pentose sugars
2
Q
NADPH
A
source of biosynthetic reducing power of fatty acids, steroid, etc.
3
Q
first phase of PPP
A
oxidative generation of NADPH; 3irreversible rxns
4
Q
second phase of PPP
A
nonoxidative interconversion of a variety of sugars; 5 reversible rxns
5
Q
fatty acid synthesis in..
A
liver, adipose tissues, and mammary glands
6
Q
steroid synthesis in…
A
adrenal gland, testes, and ovaries
7
Q
rate-limiting step of PPP
A
first reaction; G6P by glucose 6-phosphate dehydrogenase
8
Q
rate limiting step is controlled by..
A
level of NADP+
9
Q
four distinct modes of the PPP
A
- mainly ribose 5-P is needed
- both NADPH and ribose 5-P are required
- mainly NADPH is needed
- NADPH and ATP are required
