Chapter 23: Respriatory Flashcards
External respiration
exchange of gases between air spaces and blood
Internal respiration
exchange of gases between blood and tissues
Alveoli (air sacs) – sites of gas exchange;
Type I alveolar cells (simple squamous epithelium);
Type II alveolar cells (secrete surfactant to reduce surface tension)
Boyle’s Law:
“pressure of a gas (in enclosed space) varies inversely with the volume of the space”
Expiration (exhalation)
Diaphragm relaxes; As intrathoracic pressure rises, air moves out of lungs.
Tidal volume (TV)
volume of one breath (at rest, approx. 500 ml)
Respiratory rate (RR)
of breaths per minute
Minute ventilation:
total volume in/out in one minute (RR x TV)
Vital capacity
volume of a full forceful expiration following deepest inspiration
Daltons Law
A gas diffuses across a permeable membrane from an area where its partial pressure is greater to an area where its partial pressure is less
hemoglobin
reversibly binds oxygen. 1.5% of O2 in blood is dissolved in plasma, 98.5% is bound to hemoglobin
Factors which decrease the oxygen affinity of hemoglobin:
acidic environment
higher PCO2
higher temperature
Carbon Dioxide Transport
bicarbonate ion (HCO3-)
Respiratory center (medulla and pons)
controls basic respiratory rhythm