chapter 23 part 3 Flashcards
small intestine
extends from pyloric sphincter to the ileocecal value
3 subdivisions of small intestine
duodenum
jejunum
ileum
duodenum
1st portion of small intestine
most important for digestion and absorption
digestive juices of liver and pancreas empty into duodenum via
major duodenal papilla
jejunum
connects duodenum to ileum
ileum
connects small intestine to large intestine at the ileocecal valve
circular folds
permenant folding of the submucosa and mucosa
small intestine
function of circular folds
forces chyme to move slowly- increase absorptive capacity of small intestine
villi
projections of mucosa
small intestine
largest in the dudoenum
function of villi
increase surface area of small intestine to increase absorption
microvilli
villi on villi that creates a brush border
brush border enzymes
found on microvilli to complete digestion of carbohydrates and proteins
intestinal crypts
tubular glands in the walls of the small intestine
contains different types of cells that secrete products
cells of villi and crypts
enterocytes
goblet cells
enteroendocrine cells
paneth cells
stem cells
enterocytes
simple columnar cells w microvilli
secrete intestinal juice in crypts
goblet cells
mucus-secreting cells
enteroendocrine cells
release various hormones to control bile/pancreatic/intestinal juice secretion
paneth cells
release defensins and lysozyme
stem cells
continuously dividing cells that replenish mucosa
can replace any 4 above cells
segmentation
contractions in the small intestine that slow rate of movement of chyme
contractions push chyme back and forth
after a meal
parasympathetic enhances segmentation
chyme is moved slowly to increase digestion and absorption
between meals
hormone motilin releases when most absorption has already occurred
what does motiltin do
Long peristaltic waves begin in small intestine and move waste, debris, and sloughed cells toward large intestine
ileocecal valve
controls passage of materials from small intestine to large intestine
ileocecal valve closed but relaxes due to
gastroileal reflex (segmentation)
gastrin: hormone that increases small intestine motility and relaxes ileocecal valve
the large intestine
also called colon which leads to the outside
gross anatomy of the colon
teniae coli
haustra
epiploic appendages
teniae coli
bands of smooth muscle tissue from the longitudinal layer
has tone: slightly contracted at all times
pull on walls of large intestine which creates pockets
haustra
pockets formed from teniae coli
gives colon segmented appearance
contractions of individual haustra aid motility in large intestine
epiploic appendanges
fat filled pitches that hang from the surface of the large intestine
6 subdivisions of the large intestine
- cecum
- appendix
- colon
- sigmoid colon
- rectum
- anus
cecum
sac like structure making up first part of the large intestine
appendix
extends off from the cecum
lymphoid organ - MALT
stores extra bacteria: can recolonize gut when necessary
appendicitis
bacteria proliferate: appendix inflamed, swollen and becomes infected
colon
ascending colon
transverse colon
descending colon
ascending colonn
travels up right side of abdominal wall
transverse colon
crosses abdomen left to right
sharp left turn
descending colon
travels down left side of abdominal cavity
sigmoid colon
point at which colon enters the pelvis
rectum
temporary holding site for feces
contains rectal valves: prevent feces being passed with gas
anus
opens to the exterior of the body
end of the alimentary canal
two sphincters of anus
internal anal sphincter
external anal sphincter
internal anal sphincter
composed of smooth muscle
involuntary: opens/closes due to reflex
external anal sphincter
composed of skeletal muscle tissue
voluntary: decide when we use the bathroom
tissue of the large intestine
simple columnar epithelia
does digestion occur in large intestine
NO
no villi, brush border or circular folds
abundant crypts in large intestines
packed with goblet cells: mucus secreted reduces friction from movement of solid waste
importance of bacterial flora in large intestine
- vitamin synthesis: b-complex vitamins, some vitamin K synthesized by gut bacteria
- fermentation: bacteria can ferment indigestible carbohydrates and mucin
mass movements of large intestine
1.force residue toward rectum
2.promotes final drying out of feces: last water removed
3.fiber strengths mass movements and softens feces
defecation reflex
initiated by stretching of rectal walls
What happens in defecation reflex
sigmoid colon and rectum contract and internal anal sphincter relaxes
allowed by opening of the external sphincter
primary mechanism of digestion
enzymatic hydrolysis
enzymatic hydrolysis
enzymes breaks down large food molecules to monomers
add h20 to break down bonds
what enzymes are responsible for molecule breakdown
pancreatic enzymes
what is necessary for fat digestion
lipases and bile
absorption
substances must move through enterocytes from the apical membrane to basal membrane of small intestine
what substances are moved passively
nonpolar substances
sources of carbohydrates
polysaccharides
disaccharides
monosaccharides
polysaccharides
starch and glycogen found in meat
broken down into oligosaccharides: chains of 2-8 glucose molecules
disaccharides
sucrose: sugar in fruit
lactose: milk sugar
maltose: grain sugar
monosaccharides
glucose
fructose
galactose
these are the carbohydrate monomers absorbed by the small intestine
polysaccharides broken into oligosaccharides and dissacharides by
pancreatic amylase
what brush border enzymes break down oligosaccharides and disaccharides into monosaccharides
dextrinase and glucoamylase
monosaccharides transport through
enterocyte
glucose and galactose
secondary active transport
Na comes in w these substabces
fructose
facilitated diffusion
Monosaccharides exit enterocyte at
basal membrane
facilitated diffusion
sources of proteins
dietary proteins
enzyme proteins
proteins from sloughed/disintegrated mucosal cells
monomer of protein
amino acid
proteins are broken down by
pancreatic proteases
break down larger proteins into smaller fragments
trypsin and chymotrypsin
split off individual amino acids
carboxypeptides
amino acids are
transported into enterocyte via
secondary active transport
use na ion
split remaining protein fragments into individual amino acids
brush border enzymes
amino acids exit enterocute via
facilitated diffusion
sources of lipids
tryglycerides
monomer of triglycerides
fatty acids and monoglycerides