Chapter 22: Respiratory Flashcards
1
Q
What is the main purpose of the respiratory system?
A
For air to come in and go out.
2
Q
What are the 4 steps of respiratory physiology?
A
- Pulmonary ventilation
- Exchanges of respiratory gases
- Transport of respiratory gases (both oxygen and carbon dioxide) by the blood.
- Exchange of oxygen from oxygenated blood to the cells and carbon dioxide from the cells to deoxygenated blood.
3
Q
What is pulmonary ventilation?
A
Breathing
4
Q
What 2 exchanges of respiratory gases occurs?
A
- Oxygen from the lungs to deoxygenated blood.
- Carbon dioxide from the deoxygenated blood to the lungs.
5
Q
The process of the exchanging of respiratory gases is also called ____.
A
External respiration
6
Q
What part of the blood transports the respiratory gases?
A
RBCs, specifically hemoglobin transports these gases.
7
Q
The exchange of oxygen from oxygenated blood to the cells and carbon dioxide from the cells to deoxygenated blood is also called ____ or ____.
A
Cellular respiration or the Krebs’ cycle.
8
Q
What system performs steps 1 and 2 of respiratory physiology?
A
The respiratory system
9
Q
What system performs steps 3 and 4 of respiratory physiology?
A
The circulatory system
10
Q
What are the 13 structures of the respiratory system in order?
A
o (1) Nose
o (2) Nasal cavity
o (3) Pharynx (throat)
o (4) Larynx
o (5) Trachea
o (6) Right and left main/primary bronchi
o (7) Secondary bronchi
o (8) Tertiary bronchi
o (9) Bronchioles
o (10) Terminal bronchioles
o (11) Respiratory bronchioles
o (12) Alveolar ducts
o (13) Alveolus
11
Q
What 2 tracts is the pharynx common to?
A
Both the respiratory tract and digestive tract.
12
Q
How many secondary bronchi are on the right side and how many are on the left side?
A
3 secondary bronchi on the right side and 2 on the left side.
13
Q
What does the conducting zone of the respiratory system consist of?
A
It consists of passages that serve only for airflow.
14
Q
Why is from the nose to the terminal bronchioles called the conducting zone of the respiratory tract?
A
Because only air passes through. No gas exchange.
15
Q
From the ____ to the ____ is the conducting zone of the respiratory system?
A
Nose, terminal bronchioles.
16
Q
What does the respiratory zone of the respiratory system consist of?
A
It consists of the alveoli and other gas-exchanging regions of the distal airways.
17
Q
From the ____ to the ____ is the respiratory zone of the respiratory system.
A
Respiratory bronchioles, alveolus.
18
Q
Why is from the respiratory bronchioles to the alveolus called the respiratory zone?
A
Because the exchange of respiratory gases are taking place.
19
Q
What is considered the upper respiratory system?
A
The nose, nasal cavity, and pharynx.
20
Q
What is considered the lower respiratory system?
A
From the larynx to the lungs.
21
Q
What is the only external visible part of the respiratory system?
A
The nose
22
Q
What are the 3 functions of the nose?
A
Air is filtered, warmed and humidified.
It a resonating chamber for speech.
It houses the olfactory epithelium – sense of smell.
23
Q
What is the structural framework of the nose?
A
Bones and hyaline cartilage
24
Q
What are the 5 external structures of the nose?
A
- Bridge
- Root
- External Nares
- Apex
- Dorsum nasi
REMEMBER B.R.E.A.D
25
What is the root of the nose made up of?
Frontal bone
26
What bone is the bridge of the nose?
The nasal bone
27
What is the dorsum nasi of the nose?
The sharp anterior border of the nose.
28
What is the apex of the nose?
The pointed tip of the nose.
29
What is the apex flared by? What direction is it flared?
Cartilages, laterally.
30
What are the external nares?
Nostrils which are the openings on the outside.
31
What is the philtrum?
An area inferior to the nose.
32
What are the 5 internal structures of the nose?
* Floor of nasal cavity
* Midline nasal septum
* Nasal cavity
* Nasal vestibule
* Roof of nasal cavity
33
Where is the nasal cavity located?
Posterior to the external nares.
34
The nasal cavity extends from the ____ to the ____.
external nares, internal nares.
35
What is the midline nasal septum made up of anteriorly?
Nasal cartilage.
36
What is the midline nasal septum made up of posteriorly?
Vomer and perpendicular plate of ethmoid bone.
37
Where is the nasal vestibule located?
Within the nasal cavity, posterior to the external nares.
38
What does the nasal vestibule have?
Course guard hairs called vibrissae.
39
What is the function of vibrissae ?
They block small insect and debris from entering the nose.
40
What is the roof of the nasal cavity made up of?
Sphenoid and ethmoid bone.
41
What is the floor of the nasal cavity made up of?
Hard palate
42
What does the floor of the nasal cavity separate? What does this allow?
It separates the nasal cavity from the oral cavity. It allows you to breath while you chew.
43
What part of the nasal cavity is lined by olfactory epithelium?
The roof of the nasal cavity.
44
What type of epithelium is olfactory epithelium?
Pseudostratified ciliated (non-motile) columnar epithelium.
45
What sense is olfactory epithelium?
Sense of smell.
46
What is the rest of the nasal cavity lined by except for the vestibule?
Respiratory epithelium
47
What type of epithelium is the nasal vestibule lined with?
Stratified squamous epithelium.
48
What type of epithelium is respiratory epithelium?
Respiratory epithelium is pseudostratified ciliated (ciliated meaning motile, it moves) columnar epithelium with goblet cells (secretes mucus).
49
What is the chamber behind the nasal vestibule made up of?
3 folds of tissue
50
What are the 3 folds of tissue that make up the chamber behind the nasal vestibule?
Superior, middle, and inferior nasal conchae.
51
What is meatus?
The narrow air passage beneath each concha
52
What is the anatomical location of the pharynx?
It extends from the base of the skull to C4.
53
What is the pharynx?
A fibromuscular tube.
54
What do the muscles of the pharynx assist in?
They assist in swallowing and speech.
55
What is the pharynx commonly called?
The throat
56
The pharynx continues down the ____.
Esophagus
57
Why is the trachea anterior compared to the esophagus which is posterior?
We can survive without food for nearly a month. We can survive 7-10 days without water. Without air, our cells can only survive for 3-4 minutes. So, air is more important than food and water. That is why the trachea is position anteriorly (in the front).
58
What are the 3 parts of the pharynx?
Nasopharynx
Oropharynx
Laryngopharynx
59
Where is the nasopharynx located?
Posterior to the nasal cavity
60
What is the nasopharynx lined with? Why?
It is lined with respiratory epithelium because air passes through it.
61
High up on the nasopharynx wall, posteriorly is a collection of ____ called ____ or ____.
Lymphoid tissue, pharyngeal tonsil, adenoids.
62
What opens up into the nasopharynx?
An auditory/eustachian tube.
63
Surrounding the auditory/eustachian tube, there is a collection of ____ called ____.
Lymphoid tissue, tubal tonsils.
64
Where is the oropharynx located?
Posterior to the oval cavity
65
What is the oropharynx lined with? Why?
It is lined with stratified squamous non-keratinized epithelium because air and food passes through it.
66
What is at the base of the tongue?
The lingual tonsil
67
What is on the lateral walls of the oropharynx?
The palatine tonsil. ** This is the tonsil you typically think of.
68
Where is the laryngopharynx located?
Posterior to the larynx.
69
What is the laryngopharynx lined with? Why?
It is lined with a stratified squamous non-keratinized epithelium because air and water pass through it.
70
The laryngopharynx continues down (into) the ____.
Esophagus
71
The larynx is also called the ____.
Voice box
72
What is the larynx?
It's a cartilaginous tube.
73
Anatomically, where is the larynx located?
It extends from C4-C6.
74
The larynx continues down the ____.
Trachea
75
What is the main function of the larynx?
To keep food and drink out of the airway.
76
The larynx is made up of how many cartilages?
9
77
How many paired and unpaired cartilages is the larynx made up of?
3 pairs cartilages and 3 unpaired cartilages.
78
What are the 3 paired cartilages that make up the larynx?
Arytenoid
Corniculate
Cuneiform
79
What is the largest of the paired cartilages?
Arytenoid
80
What are the 3 unpaired cartilages that make up the larynx?
Thyroid
Cricoid
Epiglottis
81
Except for the epiglottis, all of the laryngeal cartilages are made up of ____.
Hyaline cartilage
82
What type of cartilage is the epiglottis made up of?
Elastic cartilage
83
Out of the 8 hyaline cartilages of the larynx, which is the largest?
The thyroid
84
What is the shape of the thyroid?
Has a shield shape.
85
Where does the thyroid fuse and what does it form?
It fuses in the midline and forms the "laryngeal prominence" or Adam's apple.
86
Why is the Adam's apple more prominent in males?
Because of the hormone testosterone.
87
At the ____ border of the thyroid cartilage, the ____ divides into the ____ and ____.
Superior, common carotid, external carotid artery, internal carotid artery.
88
From the thyroid to the ____ cartilages, seen on the posterior view, a pair of ____ are attached, and they are called ____.
Arytenoid, ligaments, vocal cords/vocal ligaments/true vocal cords.
89
The medial pair of ligaments, also called the vocal cords/vocal ligaments/true vocal cords, function in what?
They function in the production of speech.
90
What is the space between the true vocal cords called?
The glottis
91
There is a lateral pair of ligaments on the interior wall of the larynx that are called ____.
Vestibular folds/ligaments or false vocal cords.
92
What is the function of the false vocal cords.
They aid in swallowing.
93
What muscles control the vocal cords?
The deep intrinsic muscles.
94
What muscles connect the larynx to the hyoid bone?
The superior extrinsic muscles.
95
What is the epiglottis?
A flap of tissue that guards the superior opening of the larynx.
96
What is the function of the epiglottis?
It prevents food and fluid from entering the lungs and windpipe.
97
What position is the epiglottis in at rest? What does this do?
It stands almost vertically, allowing air to pass into the larynx and lungs.
98
What is the trachea also called?
The windpipe
99
What is the trachea?
A rough walled artery (air holder).
100
The trachea is anterior to the ____.
Esophagus.
101
Anatomically, where is the trachea located?
It extends from C6-T5.
102
What is the length and diameter of the trachea?
It is 12 cm long and 2 cm in diameter.
103
How many layers is the tracheal wall made up of?
3
104
What are the 3 layers of the tracheal wall?
Mucosa
Submucosa
Adventitia
105
What layer of the trachea wall is the inner lining?
Mucosa
106
What layer of the trachea wall is the middle layer?
Submucosa layer
107
What type of epithelium and connective tissue is the mucosa of the tracheal wall?
Pseudostratified ciliated columnar epithelium and areolar tissue.
108
What is the submucosa layer of the tracheal wall consist of?
Mucus secreting glands.
109
What is the submucosa layer of the tracheal wall supported by?
16-20 "C" shaped rings of hyaline cartilage, incomplete posteriorly towards the esophagus.
110
What does the gap in the C-rings (in the trachea) allow?
the gap in C-rings allows room for the esophagus to expand as swallowed food passes by.
111
What is the submucosa layer of the tracheal wall covered by?
Smooth muscle called trachealis.
112
What is the outermost layer of the tracheal wall?
The adventitia.
113
What is the adventitia layer of the tracheal wall made up of?
Collagen fibers
114
The trachea ends by dividing into what? Where does it divide at?
The right and left main/primary bronchi at T5
115
What is the last piece of the tracheal cartilage called before it divides into the left and right main bronchi?
Carina
116
What is carina?
A sensitive mucosa.
117
The right main bronchi is ____, ____, and ____ with the ____.
Shorter, wider, vertical, trachea.
118
The epithelium of the bronchial tree ____.
Changes
119
What are the epithelium changes of the bronchial tree?
The epithelium changes from pseudostratified ciliated columnar to simple columnar to simple cuboidal and then simple squamous.
120
The cartilages of the bronchial tree _____.
Change
121
What are the cartilage changes of the bronchial tree?
The cartilages changes from hyaline cartilage plates to irregular plates and no cartilage at the level of the bronchioles.
122
As the amount of cartilage ____, smooth muscle in the bronchioles ____, and this is under the control of which autonomic nervous system? The broncho ____.
Decreases, increases, sympathetic NS. Dilates
123
The lung has a ____ and an ____.
Base, apex.
124
What is the shape of the base of the lung? What is it resting on?
A broad concave portion. The diaphragm.
125
What is the apex of the lung? Where does it project?
The tip of the lung. It projects just above the clavicle.
126
The costal surface of the lung is pressed against the ____.
Ribcage
127
The mediastinal surface of the lung faces ____ towards the ____.
Medially, heart.
128
How many lobes does the right lung have?
3
129
How many lobes does the left lung have?
2
130
What is the bronchial tree?
A branching system of air tubes in each lung.
131
What blood vessels services the bronchial tree?
The brachial artery.
132
What is the serous membrane that covers the lungs?
Visceral pleura
133
Where is the parietal pleura located?
It adheres to mediastinum, inner surface of ribcage, and superior surface of the diaphragm.
134
What is the pleural cavity?
A potential space between pleurae.
135
What does the pleural cavity contain?
Pleural fluid.
136
What are the functions of the pleurae and pleural fluid?
* Reduce friction
* Create pressure gradient (lower pressure than atmospheric pressure; assists lung inflation).
137
What type of epithelium do the bronchioles have? What 2 components does the bronchiole epithelium not have?
Ciliated cuboidal epithelium. Mucous gland or goblet cell.
138
What is the first step in respiratory physiology?
Pulmonary ventilation/breathing.
139
What 2 actions are involved in pulmonary ventilation/breathing?
Inhale and exhale.
140
What type of process is inhalation?
An active process.
141
How long does inhalation last for?
2 seconds
142
What type of process is exhalation?
A passive process.
143
How long does exhalation last for?
3 seconds
144
How long is 1 respiratory rate/breath?
5 seconds
145
How many breaths are there in a min?
12-14 breaths/min.
146
What is quiet respiration?
Breathing while at rest; effortless and automatic.
147
What is forced respiration?
Deep or rapid breathing, such as during exercise or playing an instrument.
148
What are the 3 factors in pulmonary ventilation?
* Skeletal muscles of respiration
* Pressures
* Gas laws
149
What are the 2 skeletal muscles of respiration?
The diaphragm and the intercostal muscles.
150
How much of the respiration work does the diaphragm do?
2/3 or 75%
151
What nerve supplies the diaphragm?
The phrenic nerve.
152
What is the shape of the diaphragm?
Dome shaped
153
What happens when the diaphragm contracts?
It flattens down, which increases the superior inferior diameter of the thoracic cavity.
154
How much of the respiration work do the intercostal muscles do?
1/3 or 25%
155
Where are the intercostal muscles located?
Between the ribs
156
What happens when the intercostal muscles contract?
They increase the interior posterior diameter of the thoracic cavity, which increases the thoracic cavity volume.
157
What is atmospheric pressure (Patm)?
The pressure exerted by all the gases of the atmosphere.
158
What is alveolar/pulmonary pressure (Palv)?
The pressure exerted by gases in the alveolus (pressure in the lungs).
159
Alveolar/pulmonary pressure can be ____, ____, or ____ atmospheric pressure.
Equal to, lesser than, greater than.
160
What is intrapleural pressure (Pip)?
The pressure exerted by gases in the pleural cavity (pressure outside of the lungs, but in the pleural cavity).
161
Is intrapleural pressure always negative or positive?
Negative
162
What is the range of intrapleural pressure (Pip)?
-4 to -6 mm of Hg
163
What is Boyle's Law?
The pressure exerted by gases inversely related to the volume of the container. P = 1/volume.
164
What is the relationship between volume and pressure in regards to gas laws?
As the volume increases, the pressure decreases. When the volume decreases, the pressure increases.
165
At the beginning of respiration, Palv ____ Patm.
Equals
166
What is a spirometry?
It measures the amount of air in the respiratory tract.
167
What 4 volumes are measured using a spirometry?
* Tidal volume (TV)
* Inspiratory reserve volume (IRV)
* Expiratory reserve volume (ERV)
* Residual volume (RV)
168
What is tidal volume?
The amount of air passing in and out of the respiratory tract (500mL).
169
What is inspiratory reserve volume?
The max amount of air inhaled.
170
What is expiratory reserve volume?
The max amount of air exhaled.
171
What is residual volume?
The amount of air always in the lungs.
172
What 4 capacities can be calculated with a spirometry?
* Vital capacity (VC)
* Total lung capacity (TLC)
* Function residual capacity (FRC)
* Inspiratory capacity (IC)
173
What is vital capacity?
The total amount of exchangeable air.
174
What is the formula for vital capacity?
TV + IRV + ERV = VC
175
What is total lung capacity?
The maximum amount of air that the lungs can contain.
176
What is the formula for total lung capacity?
TV + IRV + ERV + RV = TLC
177
What is function residual capacity?
The amount of air remaining in the lungs after maximum expiration; the amount that can never be voluntary exhaled.
178
What is the formula for function residual capacity?
ERV + RV = FRC
179
What is inspiratory capacity?
The maximum amount of air that can be inhaled after a normal tidal expiration.
180
What is the formula for inspiratory capacity?
TV + IRV = IC
181
What is the formula for cardiac output?
Stroke volume x heart rate
182
What is the formula for minute ventilatory volume (MVV)?
Respiratory rate x tidal volume
183
What is dead air space?
The amount of air in the conducting zone of the respiratory tract.
184
____ lb of body weight = ____ ml of dead air space
1, 1
185
What is the formula for alveolar ventilation rate (AVR)?
Alveolar ventilation rate (AVR) = respiratory rate x (TV – dead space air)
186
What is Dalton's Law of Partial Pressure?
The total atmospheric pressure is the sum of the partial pressure of the individual gases.
187
What is the formula for Dalton's Law of Partial Pressure?
Patm = PN2 + PO2 + PCO2 + PH20 + P noble gases
(760 mm of Hg = 500 + 160 + 0.3)
188
What is Henry's Law of solubility?
At air water interface, the amount of gas that diffuses depends on the partial pressure and its solubility.
189
Oxygen is transported from the ____ to all the ____ of our body.
Lungs, cells
190
Carbon dioxide is transported from the ____ to the ____.
Cells, lungs
191
What color is oxygenated blood? Where is it seen?
It’s bright red and is seen in the arteries.
192
What is blood in the arteries called?
Arterial blood
193
What color is deoxygenated blood? Where is it seen?
It’s dark red and is seen in the veins.
194
What is blood in the veins called?
Veinous blood.
195
What is the volume of blood in an adult human?
4 to 6L of blood.
196
What are the functions of RBCs?
Carry oxygen from the lungs to the cells/tissues and pick up CO2 from the cells/tissues and brings it to the lungs.
197
____ of RBC cytoplasm is filled with a protein called ____.
33%, hemoglobin (Hb)
198
How many oxygen molecules can 1 hemoglobin carry?
4 oxygen molecules
199
Hemoglobin simultaneously carries ____ and ____.
Oxygen, carbon dioxide
200
What is the structure of a hemoglobin?
Hemoglobin is made up of heme and globin. Heme is made up of iron (Fe) placed within a ringlike structure. Globin is the protein, made up of alpha and beta chains.
201
Each Hb molecule consists of how many protein chains? What are they called?
4, globins
202
How many alpha chains and beta chains does an adult Hb have?
2 alpha chains (alpha 1, alpha 2) and 2 beta chains (beta 1, beta 2).
203
What are the oxygen molecules attached to on a hemoglobin?
Attached to the iron molecule.
204
What is the carbon dioxide attached to on a hemoglobin? What is this called?
Attached to the globin chains. This is called carbamino hemoglobin.
205
The bond between hemoglobin and oxygen is ____ and ____.
Loose, reversible
206
Barometric pressure = ____.
Atmospheric pressure
207
What is systemic gas exchange?
The unloading of oxygen and loading of carbon dioxide at the systemic capillaries.
208
What are the 9 functions of the respiratory system?
1. Gas exchange
2. Communication
3. Olfaction
4. Acid-base balance
5. Blood pressure regulation
6. Platelet production
7. Blood and lymph flow
8. Blood filtration
9. Expulsion of abdominal components
209
What is the gas exchange function of the respiratory system?
It provides for oxygen and carbon dioxide exchange between blood and air.
210
What is the communication function of the respiratory system?
It serves for speech and other vocalization (laughing, crying).
211
What is the olfaction function of the respiratory system?
It provides the sense of smell.
212
What is the acid-base balance function of the respiratory system?
By eliminating carbon dioxide, it helps control the pH of the body fluids.
213
What is the blood pressure regulation function of the respiratory system?
The lungs carry out a step in synthesizing angiotensin II, a hormone that regulates blood pressure.
214
What is the platelet production function of the respiratory system?
More than half of one's blood platelets are made by megakaryocytes in the lungs.
215
What is the blood and lymph flow function of the respiratory system?
Breathing creates pressure gradients between the thorax and abdomen that promote the flow of lymph and venous blood.
216
What is the blood filtration function of the respiratory system?
The lungs filter small blood clots from the bloodstream and dissolve them.
217
What is the expulsion of abdominal contents function of the respiratory system?
Breath-holding and abdominal contraction help to expel abdominal contents during urination, defecation, and childbirth.
218
