Chapter 21 - Musculoskeletal And Anti-inflammatory Drugs

Question 1

Anti-inflammatory

P. 403 and 584

Answer 1

Medication used to relieve inflammation.

• In this chapter, anti-inflammatory drugs are used to treat disorders in which the musculoskeletal system is not functioning properly because of inflammation.

Question 2

musculoskeletal conditions with inflammation:

P. 403

Answer 2

• arthritis
• bursitis
• spondylitis
• gout
• muscle strains
• sprains

☆ can cause swelling, redness, heat, pain, and limited muscle and joint mobility.

Question 3

Neuromuscular blocking agents (NMBAs)

P. 403

Answer 3

Used during surgical, endoscopic, or Orthopedic procedures.

• These drugs are potentially very dangerous and can result in respiratory arrest because of potential to paralyzed the major muscle of ventilation, the diaphragm.

☆ these are administered only by anesthesiologists or specially trained Personnel skilled in intubation, medically induced paralysis, and resuscitation.

Question 4

Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

P. 403-404

Answer 4

Such as ibuprofen, inhibit the synthesis of prostaglandins, substances responsible for producing much of the inflammation and pain of rheumatic conditions, sprains, and menstrual cramps.

Question 5

Osteoporosis

P. 408-409

Answer 5

(Porous Bone) is defined as a systemic skeletal disease characterized by low bone mass and deterioration of bone tissue, leading to Bone fragility and entry susceptibility to fracture, especially of the hip, spine, and wrist.

Question 6

Osteoporosis therapy

P. 408-409

Answer 6

Includes calcium and vitamin D supplementation and several prescription medications currently approved for the prevention and or treatment of osteoporosis.

Question 7

Hormone replacement therapy (HRT)

P. 410

Answer 7

Estrogen with or without progestin – is recommended for postmenopausal osteoporosis prevention secondary to estrogen deficiency only when the patients are unable to take other agents and when the benefits outweigh risks.

• the FDA recommends prescribing the lowest possible dose for the shortest period of time.

☆ If HRT is started soon after menopause, estrogen prevents The Accelerated phase of the bone loss that occurs in the first 5 years after the onset of menopause.

Question 8

Skeletal muscle relaxants

P. 401 and 594

Answer 8

Medications used to treat some musculoskeletal disorders associated with pain, spasms, abnormal contraction, or impaired mobility.

Question 9

Disorders of the musculoskeletal system are rather common. Drugs used to treat such conditions may be classified into two broad categories:

(P. 400)

Answer 9

1. Skeletal muscle relaxants

2. Nonsteroidal Anti-inflammatory drugs (NSAIDs)