Chapter 18: Immune Disorders

Question 1

Hypersensitivity

Answer 1

Overzealous immune responses to harmless foreign material

Question 2

Type 1: Immediate

Answer 2

• immediate response to allergen
• also called anaphylactic
• reagin: IgE class

Question 3

Mechanism of activation

Answer 3

• 1st exposure to allergen: makes IgE antibodies that bind to mast cells and basophils. These cells become sensitized
• 2nd exposure to allergen: degranulation occurs and histamine is released by basophils and mast cells

Question 4

Localized anaphylaxis

Answer 4

• Not life threatening

- Allergy (itchy rash, hives, runny nose)

Question 5

Generalized anaphylaxis

Answer 5

• Systemic reaction
• Life threatening
• Causes anaphylactic shock (blood vessels dilate, blood pressure drops, airways constrict)