chapter 18 - development of a human foetus Flashcards

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1
Q

what are changes in the mother that occur

A
  • mood swings: hormones or fear of what pregnancy brings
  • bigger abdomen: due to uterus enlargements, other organs being forced up / out
  • breast enlargement: due to hormone secretion
  • heart / blood volume: increases (to cater for extra blood to placenta)
  • urine production: increases due to increased flow to kidneys
  • bladder: first 3 months uterus presses on bladder -> urination, then uterus moves up -> less urination, end of pregnancy foetus applies pressure -> increased urination
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2
Q

what is the foetal period

A
  • week 9 (start of month 3)-birth
  • characterised by increase in size and maturation of organs
  • foetus grows from 3->50cm, weight increases from 4->3000g, proportions change
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3
Q

what is a healthy pregnancy

A
  • achieving the goal that ones baby is born healthy, the mother needs to look after their own baby
  • increased nutrients, balanced diet, weight gain, avoiding chemicals, exercise and progesterone
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4
Q

how does increased nutrients ensure a healthy pregnancy

A
  • causes increased blood flow through the placenta, increased blood flow (increased by 40% by end of pregnancy)
  • functions slow down -> nutrients stay in blood longer -> increases diffusion across placenta, may lead to constipation
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5
Q

how does a balanced diet, weight gain and avoiding chemicals ensure a healthy pregnancy

A
  • BD: increased energy intake (~850kJ / day), increased protein intake (~65g / day), increased calcium, iron, folic acid (folate), fluoride if not in water already
  • WG: ~0.5kg / week (2nd half), foetus (3.4kg), placenta (0.7kg), amniotic fluid (1kg), increased blood volume (1.6kg), tissue fluid (1.6kg), uterus (1kg), fat (3.2kg) breasts (0.9kg) = 13.4kg
  • AC: mother should not smoke, or consume alcohol or drugs
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6
Q

how doses exercise ensure a healthy pregnancy

A
  • maintaining normal work out, walking regularly, vigorous exercise -> woman carry to full term
  • allows mother to maintain stamina during labour and will get back into shape more quickly after birth
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7
Q

how does progesterone ensure a healthy pregnancy

A
  • placenta is the major source of progesterone, maintains pregnancy
  • increased progesterone prevents premature shedding of uterine lining -> can lead to premature delivery or a miscarriage
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8
Q

what are congenital disorders

A
  • defects or diseases that are present at birth, can be due to inheritance of defective genes, mutations of genes and environmental factors
  • teratogenic agent: one that causes physical defects in the developing embryo
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9
Q

how do infections disrupt normal foetal development

A
  • some viruses can cause birth defects, while others cause congenital disorders
  • rubella: viral infection, frequently contracted by school aged children, however if contracted by a pregnant woman disastrous consequences (deaf, blind, heart , malformations)
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10
Q

how does maternal diet disrupt normal foetal development

A
  • important factor in normal foetal development
  • folic acid: required for normal cell division, lack of folic acid before or during pregnancy can result in Spina bifida
  • eating whole grains, green vegetables, cereals, take folic acid one before and three months during pregnancy
  • calcium / vit. A: normal bone / cell growth, balanced diet, take vit A in last 10 weeks
  • listeria infection: can cause miscarriages or still births, avoid eating pre-packed salads, soft cheese, pate, raw / smoked seafood, eat freshly prepared food
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11
Q

how does alcohol disrupt normal foetal development

A
  • suspected teratogen, relationship has been found between alcohol intake and malformations
  • foetal alcohol syndrome: describes effects of foetal exposure to alcohol (birth weight is lower, slower growth, small head, defects of heart, malformed limbs, mental retardation)
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12
Q

how does smoking and chemicals disrupt normal foetal development

A
  • S: results in lower birth weight, addictions can be passed on to offspring, risk of abortion, gastrointestinal problems, respiratory probers, links to sudden infant death syndrome (SIDS)
  • C: besides alcohol and smoking there are other teratogenic agents
  • thalidomide: originally developed as a sleeping pill effective in preventing morning sickness, causes limb malformation, acts on limbs between the 28th-42nd day (limbs start developing at 10 days), it is now used to treat leprosy and some blood cancer
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13
Q

what is an ultrasound

A
  • a probe that is placed on the abdomen and sound waves are reflected by the foetal tissue to obtain a visual ‘echo’
  • fed into computer to produce an image
  • malformations of brain, head and limbs can be detected
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14
Q

what is a fetoscopy

A
  • involves looking directly at the foetus through the fetoscope (small telescope like instrument)
  • detects cleft lip, palate, abnormal ears, deformed / absent limbs, Spina bifida
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15
Q

what is foetal monitoring

A
  • regular recording of the babies heart rate, tales place during labour / birth using ultrasound or electrocardiography (records electrical changes)
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16
Q

what is biochemical analysis

A
  • assessment of maker proteins (phenylketonuria)

- occurs with all new borns in Australia

17
Q

what are dna probes

A
  • enables detection of a range of genetic disorders
  • DNA segments are ‘labelled’ and then attach to identical set antes of DNA to determine whether there is a ‘gap’ in the DNA being tested
18
Q

what happens during month 3 (end of first trimester)

A
  • posture more upright, hair, nails, limbs well developed, eyes closed, sex apparent
  • 4g and 3cm
18
Q

what happens during the second trimester (weeks 13-27 or months 4-6)

A
  • foetus moves / stretches limbs, kicking and turning, skeleton completed, hair covered body, gripping reflexes, digestive glands begin to function
  • 100-680g and 18-35cm
18
Q

what happens during the third trimester (weeks 28-birth around 40-42 or months 7-9)

A
  • all systems functioning except respiratory, accumulation of fat beneath skin, eyes open, body hair sheds, antibodies diffuse from mother
  • 1000-3300g and 25-50cm
18
Q

what are two ways to analyse chromosomes

A

amniocentesis: performed on women at higher risk, involves removal of amniotic fluid
- detects Spina bifida, Down syndrome, cystic fibrosis, Tay-sach
chorionic villus sampling (CVS): specimen of foetal cells are removed from chorion
- allows early termination, detects genetic / biochemical abnormalities (not Spina bifida)
foetal blood sampling: detects biochemical disorders, occurs early in the pregnancy