Chapter 16: Antiinflammatory, Antiarthritis, and Related Agents Flashcards
analgesic
compound with pain-blocking properties, capable of producing analgesia
antiinflammatory agents
drugs that block the effects of the inflammatory response
antipyretic
fever-blocking property; often achieved by direct effects on the thermoregulatory center in the hypothalamus or by blockade of prostaglandin mediators
ehrysotherapy
treatment with gold salts in which gold is taken up by macrophages, which then inhibit phagocytosis; it can be very toxic and is reserved for use in patients who are unresponsive to conventional therapy
disease-modifying antirheumatic drugs (DMARDs)
class of medications that are designed to treat inflammatory arthritis disease processes; they can also help to treat some connective tissue disorders, inflammatory bowel disease, and some cancers
gout
disorders that are related to increased blood uric acid and urate crystal deposits in joints and kidneys
inflammatory bowel disease
two disorders (Crohn’s disease and ulcerative colitis) that both are characterized by chronic inflammation of the gastrointestinal tract; they are related but also have unique characteristics
inflammatory response
the body’s nonspecific response to cell injury, resulting in pain, swelling, heat, and redness in the affected area
nonsteroidal antiinflammatory drugs (NSAIDs)
drugs that block prostaglandin synthesis and reduce inflammation, as well as have antipyretic and analgesic properties
salicylates
salicylic acid compounds, used as antiinflammatory, antipyretic, and analgesic agents; they block the prostaglandin system
salicylism
syndrome associated with high levels of salicylates–dizziness, ringing in the ears, difficulty hearing, nausea, vomiting, diarrhea, mental confusion, and lassitude
