Chapter 14: Antineoplastic Agents

Question 1

alopecia

Answer 1

hair loss; a common adverse effect of many antineoplastic drugs, which are more effective against rapidly multiplying cells, such as those of hair follicles

Question 2

anaplasia

Answer 2

a loss of cellular differentiation and organization, which leads to a loss of normal cellular function; a property of cancer cells

Question 3

angiogenesis

Answer 3

the generation of new blood vessels; cancer cells release an enzyme that causes the growth of new blood vessels (angiogenesis) to feed the cancer cells

Question 4

antineoplastic agent

Answer 4

drug used to combat cancer or the growth of neoplasms

Question 5

autonomy

Answer 5

loss of the normal controls and reactions that inhibit growth and spreading; a property of cancer cells

Question 6

bone marrow suppression

Answer 6

inhibition of the blood-forming components of the bone marrow; a common adverse effect of many antineoplastic drugs, which are those in bone marrow, seen in anemia, thrombocytopenia, and leukopenia

Question 7

carcinoma

Answer 7

tumor that originates in epithelial cells

Question 8

metastasis

Answer 8

ability to enter the circulatory or lymphatic system and travel to other areas of the body that are conducive to growth and survival; a property of cancer cells

Question 9

neoplasm

Answer 9

new or cancerous growth; occurs when abnormal cells have the opportunity to multiply and grow

Question 10

sarcoma

Answer 10

tumor that originates in the mesenchyme and is made up of embryonic connective tissue cells