Chapter 16 Flashcards
Biological treatments
Involve use of drugs, electroconvulsive therapy (ECT), brain surgery or other methods that affect body or brain chemistry
Can be effective, because many disorders have a biological basis
Placebo
a substance with no chemical effects given to a patient instead of a drug
Biological Treatments - Concerns
Increasing off-label prescription
Side effects may feel worse than the disorder symptoms
Especially bad with Lithium and antipsychotics, leading to high relapse and dropout rates
Long-term effects
Addiction
Diabetes
Tardive dyskinesia
Psychosurgery
Any surgical procedure that destroys selected areas of the brain believed to be involved in emotional disorders or violent, impulsive behavior
Frontal lobotomy
Destroys or separates parts of the frontal lobes
Stops strong emotional reactions, leads to flat affect
Also can interfere with other frontal lobe functions – planning, socially appropriate behavior
18,000 conducted 1939-51
Antonio Moniz’ method
Moniz’s hypothesis was that, in mentally ill patients, the presence of abnormal neural connections originate from the frontal lobes. Working at the University of Lisbon, Moniz believed that certain obsessive and melancholic persons could be helped if their frontal lobes were cut out.
Moniz received the 1949 Nobel Prize in Physiology or Medicine.
Walter Freeman’s method
transorbital lobotomy which cuts out parts of the frontal cortex where he claimed he no longer needed a drill, sterile field nor surgical scrubs.
Electroconvulsive Therapy (ECT)
Used in cases of severe major depression
Ineffective for other conditions
Initiated by Ugo Cerletti in 1937
Produces retrograde amnesia for the procedure itself
Widely used today (100,000+ / year)
Criticized as a tool more of control than treatment
Antipsychotic Drugs
Block or reduce sensitivity of brain receptors that respond to dopamine
Some increase levels of serotonin, a neurotransmitter that inhibits dopamine activity
Can relieve positive symptoms of schizophrenia but are ineffective for or even worsen negative symptoms
Side effects include weight gain, diabetes
Increasingly prescribed off-label (e.g. Seroquel)
Antidepressants
Monoamine oxidase inhibitors (Nardil, Parnate)
Elevate norepinephrine / serotonin in brain by blocking an enzyme that deactivates them
Tricyclic antidepressants (Elavil, Tofranil)
Boost norepinephrine and serotonin in brain by preventing normal reuptake of these substances
Selective serotonin reuptake inhibitors (SSRIs)
Also inhibit re-uptake of serotonin to boost levels
Examples – Prozac, Zoloft, Paxil
Anti-Anxiety (Tranquilizers)
Increase levels of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter
Developed for shorter-term use, with high relapse rates when people stop taking them
Often overprescribed by general physicians for patients who complain of any mood problems
Overprescription or long-term use can lead to addiction
Examples – valium, xanax
Psychodynamic Therapy
Uses various techniques to explore the unconscious as a route to identifying and solving problems
Behavioral Methods
Apply principles and techniques of classical and operant conditioning to help people change self defeating or problematic behaviors
Free Association
A method of uncovering unconscious conflicts by saying freely whatever comes to mind
Transference
A critical step in which the client transfers unconscious emotions or reactions onto therapist (e.g. conflicts about parents)