Chapter 16 Flashcards
What is the cell cycle?
A series of events that leads to cell division. For eukaryotes, it involves a series of phases in which a cell divides by mitosis or meiosis.
What is cytogenetics?
The field of genetics that involves the microscopic examination of chromosomes.
What is a karyotype?
A photographic representation of the chromosomes from an actively dividing cell. A karyotype reveals the number, size, and form of chromosomes found within an actively dividing cell.
What are sister chromatids?
The two duplicated chromatids that are still joined to each other after DNA replication.
What are sex chromosomes?
A distinctive pair of chromosomes that are different in males and females of some species and determine the sex of an individual.
What are autosomes?
All of the chromosomes found in the cell nucleus of eukaryotes except for the sex chromosomes. Humans have 22 autosomes.
What are diploid cells?
Cells containing two sets of chromosomes; designated as 2n.
What are haploid cells?
Cells containing one set of chromosomes; designated as 1n.
What is a homolog?
A member of a pair of chromosomes in a diploid organism.
What does homology mean?
A similarity that occurs due to descent from a common ancestor.
Are the X and Y chromosomes considered homologous chromosomes?
No, X and Y chromosomes differ greatly in size and genetic composition, although they do share some short regions of homology.
Phases of the cell cycle (in order):
Interphase, Prophase, Prometaphase, Metaphase, Anaphase, Telophase
Interphase
The portion of the cell cycle consisting of the G1, S, and G2 phases, during which the chromosomes are decondensed and found in the nucleus.
What is G0?
G0 is a nondividing phase. An alternative to starting G1 in the cell cycle, a cell may postpone cell division, and in some cases it never divides again.
What is mitosis?
In eukaryotes, the process in which nuclear division results in two nuclei, each of which receives the same complement of chromosomes.
What is cytokinesis?
The division of the cytoplasm to produce two distinct daughter cells.
What factors determine whether or not a cell will divide?
External factors include environmental conditions and signaling molecules. Internal factors include cell cycle control molecules and checkpoints.
What is a cyclin?
A protein responsible for advancing a cell through the phases of the cell cycle by binding to a cyclin-dependent kinase.
What is cyclin-dependent kinase (cdk)?
A protein responsible for advancing a cell through the phases of the cell cycle. Its function is dependent on the binding of a cyclin.
How is cell division regulated during G1?
During G1, the amount of a particular cyclin termed G1 cyclin increases in response to sufficient nutrients and growth factors. G1 cyclin binds to cdk. Once activated, cdk functions as a protein kinase that phosphorylates other proteins needed to advance the cell to the next phase in the cell cycle.
What are checkpoints during cell division?
One of three critical regulatory points found in the cell cycle of eukaryotic cells. At these checkpoints, a variety of proteins act as sensors to determine if a cell is in the proper condition to divide.