Chapter 15 Flashcards
brain of adults and older adults retain
the ability to adapt and change (plasticity)
PA is beneficial for
cognition in general and specially executive functions
ex of executive functions
working memory (phone number) episodic memory (what happened on the wknd) goal setting (what to do today) sustaining attention (reading) switching task (making supper and doing dishes)
what two parts of the brain decay in late adulthood
hippocampus and basal ganglia
Randomized control trial
60-75 year old walking group/controlled group 6 months cognitive and physical assessment improved cognitive function -frequent walking
aerobic fitness and brain
- VO2 max peek
2. volume hippocampus
meta analysis of aerobic fitness and brain
consistent with previous study
general effect- cognition
special effect- executive function
(hippocampus and frontal lobes)
how much PA is need for aerobic fitness and brain
moderate activity
3 days a week for 6 months
also benefits higher intensity
a few intervention studies also have found mild cognitive impairments and Alzheimer
6 month intervention
mixed results- overall improvement
older adults with demetia
1) increase cognition
2) grey and white matter increase
3) improved brain function
plausible mechanism three levels
- molecular mechanism
- cognitive mechanism
- socioemotional mechanism
molecular mechanisms
-voluntary exercise in animals 3 main options: 1. neurogenesis 2. angiogenesis 3. increased neurotransmitter and neurotrophic factors brain- derived neurotrophic
morris water maze
learning a maze requires animal to use hippocampus
rat in maze, find board
learn the task faster when they have a wheel
animal models
animal models for alzhemiers for reduced presence of disease
animal model for parkinson also show benefit for exercise
evidence (from animal studies) for
neurogenesis
new neurons and better survival in
hippocampus
young and older animals
old do improve
evidence for angiogenesis with
exercise (may not protect against stroke)
cognitive neuron science
early evidence
better communication between brain areas
older adults with higher VO2 max had better connectivity between brain areas
white matter also increases with PA
increase connectivity related to better performance on executive function tasks
in humans PA..
1) increase communcations between brain area
2) enhances vasculature
3) improves how frontal cortext functions
4) reduce prevalance of alzhiemers
more fit people =
more grey matter
socioemotional mechanism
exercise –> mood
mood –> cognition
exercise –> mood –> cognition
what we dont know about PA and cognition
new area, alot more that is unknown
early evidence that PA improves cognition
early evidence that PA may minimize age- related and disease related decline
anti-depressant
treat attention defict hyperacticity disorder
- autism spectrum disorder
- prevent / treat alzheimers
- parkison disease
- early evidence improved exective function and motor control