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Drugs and Human Behavior final > Chapter 15 > Flashcards

Chapter 15 Flashcards

Marijuana

1
Q

What are the three cannabis plants?

A
  • C. Stative
  • C. Indica
  • C. Ruderalls
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2
Q

What do you know about C.Sativa?

A
  • George Washington used it as a really good fiber for making rope
  • 1% THC content
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3
Q

What do you know about C. Indica?

A
  • It grows all over
  • Its higher in THC content at 6-7% THC.
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4
Q

What do you know about C. Ruderalls?

A
  • grows in Russia
  • even more THC (6-7%)
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5
Q

what is interesting about cannabis plants growing next to each other?

A

Different plants growing next to each other can have different levels of THC content

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6
Q

What was the earliest use of Marijuana?

A

Around 2700 B.C. in China.

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7
Q

Harry J. Anslinger

A

He was the first commissioner of the deferral bureau of narcotics (1932-1962)

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8
Q

below 15 mgs do you see a lot of affects on Marijuana users?

A

no

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9
Q

What physiological effects are seen in marijuana users at high doses? (>15mgs)

A
  • **increased heart rate (most profound effect of THC)
  • increase appetite
  • mild analgesia (decrease pain)
  • **decrease ocular pressure (pressure on the eyes that can cause blindness)
  • **decreases nausea during chemotherapy.
  • mild anticonvulsant
  • may decrease panic attack
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10
Q

There were _____ legal medical preparation on the market until_________ was passed?

A

A: 28; 1937 Tax Act

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11
Q

Where did marijuana start?

A

China

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12
Q

What is the duration of marijuana

A

smoked: 2-5 hours
ingested: 4-6 hours

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13
Q

What is the dosage of Marijuana

A

about .5 mgs per joint

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14
Q

what is CB1

A

presynaptic

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15
Q

does the fetal brain have CB1 receptors?

A

yes

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16
Q

if there is a withdrawl symptom there is..

A

dependence

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17
Q

what is teh absorbtion rate of marijuana?

A

smoked=immediate
injested=2hours

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18
Q

what are the effects of 2-5mgs of marijuana?

A

mild euphoria

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19
Q

what was the issues with Colorado legalizing marijuana?

A
  • kids in the hospital
    -people shipping marijuana illegally
  • pets eating it
  • candy look alikes
20
Q

how long does marijuana metabloite stay in the body after one exposure?

A

30 days

21
Q

effects of 6-17mgs of marijuana

A

perceptual and time distortion

22
Q

what are the effects of 18-25 mgs of marijuana?

A

delusions and hallucinations

23
Q

When was THC isolated?

A

1964

24
Q

Is there a synthetic THC on the market?

A

yes

25
Q

When was the Endogenous Neurotransmitter, and what is it?

A

The mid 80s and its the neurotransmitter that looks like marijuana in the brain.

26
Q

What is the most profound effect of THC?

A

increased heart rate

27
Q

How does marijuana help durning chemotherapy?

A

It decreases nausea that is caused with use of chemotherapy.

28
Q

Is there more CB1 or CB2?

A

There is more CB1

29
Q

What are the two receptors that THC and other cannabinoids bind to?

A

CB1 and CB2,both G-protien coupled.

30
Q

Where are CB2 receptors found?

A

Outside of the brain in immume cells, (this suggests that cannabinoids may play a role in the modulation of the immune response)

31
Q

What are CB1 receptors ann where are they found?

A

What marijuana attaches to and they are found throughout the body but primary in the brain.

32
Q

What is the difference between smoking and ingesting marijuana?

A

Smoking is immediate, ingestion is slower.

33
Q

How does the location of CB1 receptors in the brain provide some clues on their functions?

A

The CB1 receptors impact the nucleus accumens which is involved in reward, which points to how marijuana promotes feeling of reward.

34
Q

Does the fetal brain contain CB receptors?

A

Yes, found in the cerebellum and cortex

35
Q

Are there sex difference with the efffects of THC?

A

Yes, in the entiociceptive effects of THC there are sex differences.

36
Q

What are some health concerns with Mairjuana?

A
  • Carbon monoxide in the smoke (low baby birth wieght)
  • metabolites stay in the body a long time
  • small decrease in testosterone for males.
  • Herbicides in illegally grown marijuana
37
Q

Is there a sex difference in analgesia (pain reduction) in studies on marijuana in rats.

A

females have a slightly higher level of analgesia than the males in rats.

38
Q

The LaGuardia Report

A

The only psychological negative effect they found consistency in was “amotivational syndrome”.

39
Q

What did the commission of the LaGuardia Report recommend about marijuana?

A

Decriminalization of marijuana

40
Q

What does tolerance look like with marijuana?

A

** its the oposite of tolerance as the more often you smoke the less you need to get a continued high. The most often you smoke, the more is in your blood as t can stay there for 30 days.

41
Q

what does dr havens think about early studies in england about brain damage with MJ?

A

there is not a lot of evidence

42
Q

what is consistently the physiological effect observed after smoking marijuana or ingesting marijuana?

A

increased heart rate and redding of the eyes.

43
Q

THC has a long _________ of elimination, and its metabolites can be found in the body for up to severall weeks after THC enters the body.

A

half-life

44
Q

Selective THC receptors exist in brain tissue, leading to the discovery of a naturally occurring brain cannabinoid called what?

A

amandamide

45
Q

What are three ways Marijuana is useful in medical settings?

A
  • Treatment of glaucoma
  • reduction of nausea in chemotherapy patients.
  • Increase of appetite in AIDS patients.
46
Q

Although high addiction rates are not common, does addiction occur in some individuals?

A

yes, whenever there are withdrawal symptoms we see addiction.

47
Q

what do we know about marijuana and driving?

A

Marijuana can impair driving skills but it is not clear that smoking marijuana leads to an increased frequency of accidents.

Drugs and Human Behavior final (7 decks)

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