Chapter 15 Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

mechanism of pathogenicity

A

how we get sick

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

pathogens use…

A

portal of entry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is a critical early step for pathogens

A

adherence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

key portals of entry

A

mucus membranes (respiratory, digestive, genitourinary)

skin

parental route (bypasses skin and mucus membrane, BITES)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

portal of exit is usually the same as…

A

portal of entry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what are the most common portals of entries

A

mucus membranes of respiratory, digestive, and urinary systems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

example of parenteral route

A

broken skin, bite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are TORCH infections

A

organisms that cross the placenta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

T in TORCH stands for..

A

Toxoplasmosis gondii - found in cat feces, why women are supposed to avoid kitty litter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

R in TORCH stands for…

A

congenital Rubella syndrome (CRS) - can lead to deafness, cataracts, etc.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

C in TORCH stands for..

A

congenital CM, when a baby is born with cytomegalovirus infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

O in TORCH stands for…

A

other (syphilis, HIV, hep B, chicken pox, 5th disease)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

ID-50

A

infection dose - number of organisms it would take to cause infection in 50% of people

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

LD-50

A

lethal dose - how many toxins kill 50% of infected people

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

ID50 can changed based on…

A

portal of entry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

endotoxin

A

lipid membrane of gram negative bacteria

16
Q

exotoxins

A

produced by gram positive bacteria

17
Q

gram negative bacteria produce…

A

Lipid A (endotoxin)

18
Q

gram positive bacteria produce…

A

unique toxins

19
Q

endotoxins cause…

A

general symptoms

20
Q

most exotoxins are destroyed around _______

A

41 degrees C (105.8 F)

20
Q

exotoxins cause…

A

specific symptoms depending on the toxin

21
Q

endotoxins are…

A

heat stable

21
Q

example of an endotoxin surviving at higher temps

A

staphylococcus entertoxin

22
Q

exotoxins can be converted to…

A

toxoids (vaccines) and neutralized by antitoxin therapies

23
Q

LD50 for endotoxins are…

A

low

24
Q

endotoxins can induce

A

fevers