Chapter 14: Liver, gallbladder, exocrine pancreas Flashcards

1
Q

the liver is located in the ____ of the abdomen

A

RUQ

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2
Q

these two ligaments separate the large left and right lobules from each other on the liver

A

falciform/round

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3
Q

the ___ surface contains the caudate and quadrate lobules

A

visceral

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4
Q

if left untreated, patients with hepatitis C will develop _____

A

cirrhosis

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5
Q

the ____ is located on the posterior surface of the liver

A

gallbladder

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6
Q

the central vein, hepatic artery, and bile duct are all three together known as the ___ ___.

A

portal triad

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7
Q

terminal branches of portal veins empty into ___ ____.

A

hepatic sinusoids

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8
Q

the two main functions of the liver include ____ the ___ and produce ___.

A

cleanse, blood, bile

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9
Q

one unique feature of the liver includes a ___ blood supply from the GI tract (___%) and hepatic arteries(___%)

A

dual, 75, 25

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10
Q

this is another name for the connective tissue that covers the portal triad

A

portal tract

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11
Q

these small ducts drain canaliculi approaching each lobule

A

Canals of hering

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12
Q

Canals of hering eventually drain into ___ ___ ___

A

larger bile ducts

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13
Q

the narrow fluid-filled perivascular space separating the endothelial lining of sinusoids is known as the ___ _ ____

A

Space of Disse

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14
Q

this zone of the acinus is usually used for alcohol detoxification

A

zone 3

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15
Q

the connective tissue layer that encapsulates the liver is known as

A

Glisson capsule

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16
Q

where it faces the peritoneal cavity, the glisson capsule is covered with

A

serous mesothelium

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17
Q

polyhedral parenchymal cells that are arranged in irregular plates between hepatic sinusoids are known as

A

hepatocytes

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18
Q

three functional surfaces of hepatocytes include:

A

canicular surface, sinusoidal surface, and a middle surface between the two

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19
Q

the absorptive surface of the hepatocyte is studded with ____ that face the space of disse

A

microvilli

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20
Q

fatty liver occurs when the organ fills with ___ ____, forms _____, and can be secondary to chronic alcoholism

A

lipid droplets, adipocytes

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21
Q

____ cells are specialized immunity cells for the liver that have phagocytic properties and remove bacteria, virus, and tumor cells to protect the liver.

A

Kupffer

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22
Q

Kupffer cells have abundant ___ and ___ on their surfaces

A

filopedia, microvilli

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23
Q

the long microvilli that project into the space of disse ___ ___ ___ and enhance the rate of ____

A

increase surface area, metabolites

24
Q

these cells found in the space of disse secrete growth factors, cytokines, and extracellular matrix proteins

A

Ito cells

25
Q

these star shaped cells in the space of disse store and regulate 80% of total ____ in the body via ___ ____.

A

retinoids, lipid droplets

26
Q

the liver is well known for being rich in vitamin __.

A

A

27
Q

the smallest intrahepatic ducts have one layer of ___ ___ _____surrounding a small lumen.

A

small cuboidal cells

28
Q

as ducts get larger in the liver, the cells become ____

A

columnar

29
Q

the bile duct is made up of ___ ___ epithelia

A

simple columnar

30
Q

detoxified waste for elimination via alimentary canals is known as

A

bile

31
Q

to prevent bile leakage, the lateral borders of hepatocytes are reinforced with ____ & ___ _____.

A

desmosomes and tight junctions

32
Q

the hollow, pear shaped organ lying in the shallow fossa on the inferior surface of the liver is the ____.

A

Gallbladder

33
Q

three parts of gallbladder:

A

fundus, body, neck

34
Q

the function of the gallbladder includes storing ___ and concentrating it by absorbing _____ & ______.

A

bile, water, electrolytes

35
Q

the gallbladder is connected to the liver and duodenum by the ____ ___ ____.

A

biliary duct system

36
Q

the gallbladder drains through the ___ ___.

A

cystic duct

37
Q

the cystic duct joins the ___ ____ ___ to form the common bile duct

A

common hepatic duct

38
Q

three layers of gallbladder include:

A

mucosa, muscularis, and serosa

39
Q

the gallbladder is made of ___ ___ epithelium with many ____

A

simple columnar, microvilli

40
Q

the mucosa of the gallbladder forms ____

A

ridges

41
Q

the outer layer of the gallbladder includes ___, ___ ___, and a rich lymphatic plexus

A

nerves, blood vessels

42
Q

___ is released from the GB by reflex contraction of smooth muscle in response to the hormone _____.

A

Bile, cholecystokinin

43
Q

this accessory digestive gland is located on the posterior wall of the abdominal cavity, in the retroperitoneal position near the 1st and 2nd lumbar vertebrae

A

pancreas

44
Q

the head of the pancreas lies in the ___ of the _____

A

concavity duodenum

45
Q

the ____/___/___ extend transveresly into the spleen

A

neck, body, tail

46
Q

the ___ ____ separates the pancreas from the posterior abdominal wall

A

omental bursa

47
Q

the ___ portion of the pancreas makes up 99% of its weight is is made of ____ acini with associated ducts

A

exocrine, secretory

48
Q

__ cells produce pancreatic juice which contains ____ enzymes that empty through the excretory duct system into the ____

A

Acinar, digestive, duodenum

49
Q

the endocrine portion of the pancreas contains __ __ ___ which produce hormones that affect carbohydrate metabolism

A

islets of Langerhans

50
Q

___ cells surround islets in the pancreas

A

Acinar

51
Q

the ___ ____ ____ transverses the whole organ

A

main pancreatic duct

52
Q

the main pancreatic duct opens into the duodenum with the ___ ___

A

bile duct

53
Q

the smaller pancreatic duct receives branches from the ____

A

head

54
Q

each oval shaped acini consists of one layer of ___ ___ around a central ____

A

cuboidal cells, lumen

55
Q

examples of digestive enzymes secreted by the pancreas

A

trypsin, chymotrypsin, amylase, lipase, and carboxypeptidase

56
Q

digestive enzymes of the pancreas are secreted ____ by ____

A

exocytosis, vesicles.