Chapter 1.3.2 Macromolecules Flashcards
What are the four main classes of important molecules
- Carbohydrates
- Lipids
- Proteins
- Nucleic acids
What are macromolecules considered to be
Polymers
What is a polymer
Long molecule consisting of building blocks linked by covalent bonds
What are polymers built from
Monomers
What is a monomer
Repeating units that are the building blocks
Why are enzymes helpful for cells
Because they help making/destroying polymers by increasing the rate of reaction (most enzymes are proteins)
What does the dehydration reaction consist of
Consists of synthesizing a polymer by removing a water molecule to covalently bond 2 molecules
What does the hydrolysis reaction consist of
Consists of breaking down a polymer by adding a water molecule (reverse of dehydration)
Which of the four main important molecules is NOT a macromolecule
Lipids, too small to form polymers
What are carbohydrates
Sugars or polymers of sugars
Name the simplest form of carbohydrates
Monosaccharides (is a monomer)
What is a polysaccharide
Polymers composed of many sugars
What is most common monosaccharide
Glucose (C6H12O6)
What is the molecular composition of sugars
They’re made of at least 3 C with O and H and they’re polar
How do we name carbon chains based on their length (assuming they all end with -ose)
By using numeral prefixes such as hex for 6, tri for 3 and pent for 5 (if it ends by -ose, it’s most likely a sugar)
By what reaction do two monosaccharides form one disaccharide and what name do we use for their link
- Dehydration reaction
- Glycosidic linkage
What are the two monosaccharides that compose Maltose
Glucose + Glucose
What are the two monosaccharides that compose Sucrose
Glucose + Fructose
What are the two monosaccharides that compose Lactose
Glucose + Galactose
Name the two uses of carbs
- Storage polysaccharides
- Structural polysaccharides
The function and shapes of the polysaccharides depend on 2 things
- Their sugar monomers
- The positions of their glycosidic linkage
Is starch a storage or structural polysaccharide
Storage
Is Cellulose a storage or structural polysaccharide
Structural
What are the 2 forms of starch stored in plastids
- Amylose (simplest, unbranched)
- Amylopectin (branched)
What do animals store carbohydrates as, in their liver or muscle cells
As glycogen (branched ++)
What makes cellulose a structural polysaccharide
- Tough
- Polymer of glucose (like starch) with straight and linear linkages
What are the two different ring structures for glucose and what differentiates them
- Alpha (-OH group of first C is below plane of ring)
- Beta (-OH group of first C is above plane of ring)
In what form of ring structure does starch presents itself in
All in alpha form
In what form of ring structure does cellulose presents itself in
All in beta form
What differs between the linkages and structures of starch and cellulose
- Structure and linkages of starch are helical
- Structure and linkages of cellulose are straight and never branched
Name the parallel cellulose strands held together by H bonds in plant cells
Microfibrils
An enzyme that can hydrolyze alpha can also hydrolyze beta linkages
False
What are the cell walls of fungi made of, what structural polysaccharide
Cithin
Are lipids a group of hydro phobic or philic molecules
Hydrophobic
Why are lipids hydrophobic
- Mostly hydrocarbon bonds, not polar
- Few polar bonds with O
What are the 3 most important lipids
- Fats
- Phospholipids
- Steroids
By what reaction are large molecules of lipids assembled from smaller molecules
Dehydration reaction
What is a fat composed of
1 glycerol and 3 fatty acids
What characterize a saturated fat
- No double bonds
- As many H as possible
What characterize an unsaturated fat
- One or more double bonds
Explain why saturated fats can stay solid at room temperature
Because the flexibility from their single bonds let them pack together tightly
Explain why unsaturated fats are often liquid at room temperature
Because their double bonds prevents them from packing together tightly enough to stay solid
What is the main function of fat
Energy storage (a gram of fat store more than 2x the energy of a gram of polysaccharide like starch)
How does fat help animals other that being a source of energy
- Can cushion vital organs
- Helps insulate to keep warmer body temperature
What part of the cell do phospholipids make up
The cell membrane
How can the phospholipids self assemble into a bi-layer in water
Because one side is hydrophilic (the head) and the other is hydrophobic (tails)
What are steroids characterized by
A carbon skeleton consisting of 4 fused rings
Rearranging cholesterol can result in other steroids
True
Name examples of steroids we saw in class
- Cholesterol
- Vertebrate sex hormones
Name the 4 functions or proteins
- Enzymatic proteins : selective acceleration of chemical reactions
- Defensive proteins : protection against disease
- Storage proteins : storage of amino acids
- Transport proteins : transport of substances
Name the 4 different types of proteins
- Hormonal proteins : coordination of an organism’s activities
- Receptor proteins : response of cell to chemical stimuli
- Contractile and motor proteins : movement
- Structural proteins : support
What are the monomers of proteins called
Amino acids
What are the polymers of proteins called
Peptides or polypeptides
Define protein
Biologically functional molecule made up of one or more polypeptides
What is an amino acid composed of
- NH3+ group
- COO- group
- H atom
- R group (variant group)
What does the side chain (variable group R) does in an amino acid
Determines the characteristics of the the amino acid
What makes certain amino acids hydrophobic
Their side chains/bonds do not contain oxygen making them nonpolar
What does having O in a side bond of an amino acid do
It charges it, making it polar and hydrophilic
What is a peptide bond
Resulting covalent bond formed by the linkage of two amino acid polymers
By what type of reaction do amino acid polymers link together to form chains
Dehydration reaction
How can you recognize polypeptides
By their N terminus and C terminus
What do nucleic acids do
Store, transmit and help express hereditary information
What determines a polypeptide’s amino acid sequence
Programmed by a gene
What are the monomers of nucleic acids called
Nucleotides
What are the 2 types of nucleic acids
- DNA (deoxyribonucleic acid)
- RNA (ribonucleic acid)
If the DNA acts like a blueprint and does not carry out the activities, what does
Proteins
What are the 3 steps of gene expression
- Synthesis of mRNA in the nucleus
- Movement of mRNA into cytoplasm via nuclear pore
- Synthesis of protein using information carried on mRNA (occurs at the ribosome)
What are the 3 parts that compose a nucleotide
- Nitrogenous base
- Pentose sugar
- One or more phosphate groups
What are the 2 types of nitrogenous bases
Pyrimidines and purines
What are the nitrogenous bases in pyrimidines
Cytosine, Thymine and Uracil (in RNA)
What are the nitrogenous bases in purines
Adenine and Guanine
What nitrogenous base is exclusive to DNA
Thymine
What nitrogenous base is exclusive to RNA
Uracil
What are the components of the nucleoside
Sugar + nitrogenous base
What is the difference between the two sugar Deoxyribose (in DNA) and Ribose (in RNA)
Deoxyribose lacks an atom of O
What type of linkage join nucleotides
Phosphodiester linkages
Are nitrogenous bases part of the backbone
No
What is the structure of DNA composed of
2 polynucleotides that forms a double helix
What are the 2 DNA strands held together by
H bonds
In DNA what does A and G pairs with
T and C
What do we call the strands of DNA when we know the sequence of one strand because of the other one
That they are complementary
The amounts of the A and T(A and U in RNA) and C and G pairs are equivalent
True
RNA exists as single strands
True
What are the 3 kinds of cellular work
- Chemical : pushing endergonic/anabolic reaction (requires energy)
- Transport : pumping substances across membranes
- Mechanical : muscle contraction, movement of chromosomes during cellular reproduction
What is ATP (adenosine triphosphate)
Source of energy that powers cellular work
Eg. making RNA
What does ATP contain (3)
- Ribose
- Nitrogenous base (Adenine)
- Triphosphate (chain of 3 phosphate groups)
Why does ATP releases more energy than most other molecules
- Because all 3 phosphate groups are negatively charged so they repel each other
- Triphosphate tail acts like a compressed spring ready to be released
What is the ATP cycle
The process of coupling exergonic processes to endergonic ones
How do plants make ATP
By using light energy