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A&P > Chapter 10 - Muscle Tissue > Flashcards

Chapter 10 - Muscle Tissue Flashcards

1
Q

Acetylcholine (ACh)

A

Neurotransmitter that binds at a motor end-plate to trigger depolarization

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2
Q

Actin

A

Protein that makes up most of the thin myofilaments in a sarcomere muscle fiber

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3
Q

Action potential

A

Change in voltage of a cell membrane in response to a stimulus that results in transmission of an electrical signal; unique to neurons and muscle fibers

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4
Q

Aerobic respiration

A

Production of ATP in the presence of oxygen

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5
Q

Angiogenesis

A

Formation of blood capillary networks

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6
Q

Aponeurosis

A

Broad, tendon-like sheet of connective tissue that attaches a skeletal muscle to another skeletal muscle or to a bone

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7
Q

ATPase

A

Enzyme that hydrolyzes ATP to ADP

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8
Q

Atrophy

A

Loss of structural proteins from muscle fibers

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9
Q

Autorhythmicity

A

Heart’s ability to control its own contractions

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10
Q

Calmodulin

A

Regulatory protein that facilitates contraction in smooth muscles

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11
Q

Cardiac muscle

A

Striated muscle found in the heart; joined to one another at intercalated discs and under the regulation of pacemaker cells, which contract as one unit to pump blood through the circulatory system. Cardiac muscle is under involuntary control

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12
Q

Concentric contraction

A

Muscle contraction that shortens the muscle to a move a load

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13
Q

Contractility

A

Ability to shorten (contract) forcibly

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14
Q

Contraction phase

A

Twitch contraction phase when tension increases

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15
Q

Creatine Phosphate

A

Phosphagen used to store energy from ATP and transfer to muscle

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16
Q

Dense body

A

Sarcoplasmic structure that attaches to the sarcolemma and shortens the muscle as thin filaments slide past thick filaments

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17
Q

Depolarize

A

To reduce the voltage difference between the inside and outside of a cell’s plasma membrane (the sarcolemma for a muscle fiber), making the inside less negative than at rest

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18
Q

Desmosome

A

Cell structure that anchors the ends of the cardiac muscle fibers to allow contraction to occur

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19
Q

Eccentric contraction

A

Muscle contraction that lengthens the muscle as the tension is diminished

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20
Q

Elasticity

A

Ability to stretch and rebound

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21
Q

Endomysium

A

Loose, and well-hydrated connective tissue covering each muscle fiber in a skeletal muscle

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22
Q

Epimysium

A

Outer layer of connective tissue around a skeletal muscle

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23
Q

Excitability

A

Ability to undergo neural stimulation

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24
Q

Excitation-contraction coupling

A

Sequence of events from motor neuron signaling to a skeletal muscle fiber to contraction of the fiber’s sarcomeres

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25
Q

Extensibility

A

Ability to lengthen (extend)

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26
Q

Fascile

A

Bundle of muscle fibers within a skeletal muscle

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27
Q

Fast glycolytic (FG)

A

Muscle fiber that primarily uses anaerobic glycolysis

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28
Q

Fast oxidative (FO)

A

Intermediate muscle fiber that is between slow oxidative and fast glycolytic fibers

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29
Q

Fibrosis

A

Replacement of muscle fibers by scar tissue

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30
Q

Glycolysis

A

Anaerobic breakdown of glucose to ATP

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31
Q

Graded muscle response

A

Modification of contraction strength

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32
Q

Hyperplasia

A

Process in which one cell splits to produce new cells

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33
Q

Hypertonia

A

Abnormally high muscle tone

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34
Q

Hypertrophy

A

Addition of structural proteins to muscle fibers

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35
Q

Hypotonia

A

Abnormally low muscle tone caused by the absence of low-level contractions

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36
Q

Intercalated disc

A

Part of the sarcolemma that connects cardiac tissue, and contains gap junctions and desmosomes

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37
Q

Isometric contraction

A

Muscle contraction that occurs with no change in muscle length

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38
Q

Isotonic contraction

A

Muscle contraction that involves changes in muscle length

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39
Q

Lactic acid

A

Product of anaerobic glycolysis

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40
Q

Latch-bridges

A

Subset of a cross-bridge in which actin and myosin remain locked together

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41
Q

Latent period

A

The time when a twitch does not produce contraction

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42
Q

Motor end-plate

A

Sarcolemma of muscle fiber at the neuromuscular junction, with receptors for the neurotransmitter acetylcholine

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43
Q

Motor unit

A

Motor neuron and the group of muscle fibers it innervates

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44
Q

Muscle tension

A

Force generated by the contraction of the muscle; tension generated during isotonic contractions and isometric contractions

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45
Q

Muscle tone

A

Low levels of muscle contraction that occur when a muscle is not producing movement

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46
Q

Myoblast

A

Muscle-forming stem cell

47
Q

Myofibril

A

Long, cylindrical organelle that runs parallel within the muscle fiber and contains the sarcomeres

48
Q

Myogram

A

Instrument used to measure twitch tension

49
Q

Myosin

A

Protein that makes up most of the thick cylindrical myofilament within a sarcomere muscle fiber

50
Q

Myotube

A

Fusion of many myoblast cells

51
Q

Neuromuscular junction (NMJ)

A

Synapse between the axon terminal of a motor neuron and the section of the membrane of a muscle fiber with receptors for the acetylcholine released by the terminal

52
Q

Neurotransmitter

A

Signaling chemical released by nerve terminals that bind to and activate receptors on target cells

53
Q

Oxygen debt

A

Amount of oxygen needed to compensate for ATP produced without oxygen during muscle contraction

54
Q

Pacesetter cell

A

Cell that triggers action potentials in smooth muscle

55
Q

Pericyte

A

Stem cell that regenerates smooth muscle cells

56
Q

Perimysium

A

Connective tissue that bundles skeletal muscle fibers into fascicles within a skeletal muscle

57
Q

Power stroke

A

Action of myosin pulling actin inward (toward the M line)

58
Q

Pyruvic acid

A

Product of glycolysis that can be used in aerobic respiration or converted to lactic acid

59
Q

Recruitment

A

Increase in the number of motor units involved in contraction

60
Q

Relaxation phase

A

Period after twitch contraction when tension decreases

61
Q

Sarcolemma

A

Plasma membrane of a skeletal muscle fiber

62
Q

Sarcomere

A

Longitudinally, repeating functional unit of skeletal muscle, with all of the contractile and associated proteins involved in contraction

63
Q

Sarcopenia

A

Age-related muscle atrophy

64
Q

Sarcoplasm

A

Cytoplasm of a muscle cell

65
Q

Sarcoplasmic reticulum (SR)

A

Specialized smooth endoplasmic reticulum, which stores, releases, and retrieves Ca++

66
Q

Satellite cell

A

Stem cell that helps to repair muscle cells

67
Q

Skeletal muscle

A

Striated, multinucleated muscle that requires signaling from the nervous system to trigger contraction; most skeletal muscles are referred to as voluntary muscles that move bones and produce movement

68
Q

Slow oxidative (SO)

A

Muscle fiber that primarily uses aerobic respiration

69
Q

Smooth muscle

A

Nonstriated, mononucleated muscle in the skin that is associated with hair follicles; assists in moving materials in the walls of internal organs, blood vessels, and internal passageways

70
Q

Somites

A

Blocks of paraxial mesoderm cells

71
Q

Stress-relaxation response

A

Relaxation of smooth muscle tissue after being stretched

72
Q

Synaptic cleft

A

Space between a nerve (axon) terminal and a motor end-plate

73
Q

T-tubule

A

Projection of the sarcolemma into the interior of the cell

74
Q

Tetanus

A

A continuous fused contraction

75
Q

Thick filament

A

The thick myosin strands and their multiple heads projecting from the center of the sarcomere toward, but not all the way to, the Z-discs

76
Q

Thin filament

A

Thin strands of actin and its troponin-tropomyosin complex projecting from the Z-discs toward the center of the sarcomere

77
Q

Treppe

A

Stepwise increase in contraction tension

78
Q

Triad

A

The grouping of one T-tubule and two terminal cisternae

79
Q

Tropomyosin

A

Regulatory protein that covers myosin-binding sites to prevent actin from binding to myosin

80
Q

Troponin

A

Regulatory protein that binds to actin, tropomyosin, and calcium

81
Q

Twitch

A

Single contraction produced by one action potential

82
Q

Varicosity

A

Enlargement of neurons that release neurotransmitters into synaptic clefts

83
Q

Visceral muscle

A

Smooth muscle found in the walls of visceral organs

84
Q

Voltage-gated sodium channels

A

Membrane proteins that open sodium channels in response to a sufficient voltage change, and initiate and transmit the action potential as Na+ enters through the channel

85
Q

Wave summation

A

Addition of successive neural stimuli to produce greater contraction

86
Q

What does muscle tissue allow?

A

Active movement of the body or materials within the body

87
Q

What are the three types of muscle tissue?

A

Skeletal
Cardiac
Smooth

88
Q

By acting on the skeleton, ______.

A

most of the body’s skeletal muscle produces movement

89
Q

Where is cardiac muscle found? What does it do?

A

The heart

It pumps blood through the circulatory system

90
Q

Where is smooth muscle found?

A

The skin, walls of internal organs, blood vessels, and internal passageways

91
Q

What is smooth muscle associated with in the skin?

A

Hair follicles

92
Q

What does skeletal muscle contain?

A

Connective tissue
Blood vessels
Nerves

93
Q

What are the three layers of connective tissue?

A

Epimysium
Perimysium
Endomysium

94
Q

What are skeletal muscle fibers organized into groups of?

A

Fascicles

95
Q

How do muscles attach to bones?

A

Directly or through tendons or aponeuroses

96
Q

What does skeletal muscle do?

A

Maintains posture, stabilize bones and joints, controls internal movement, and generates heat

97
Q

Are skeletal muscle fibers long or short?

A

Long

98
Q

Are skeletal muscle fibers single- or multi-nucleated

A

Multinucleated

99
Q

What is the sarcolemma?

A

The membrane of the skeletal cell

100
Q

What is the sarcoplasm?

A

The cytoplasm of the skeletal cell

101
Q

What is the sarcoplasmic reticulum (SR)?

A

A form of endoplasmic reticulum

102
Q

What are skeletal muscle fibers composed of?

A

Myofibrils

103
Q

What creates the striations of skeletal muscle?

A

Organization of actin and myosin resulting in the banding pattern of myofibrils

104
Q

What is a sarcomere?

A

The smallest contractile portion of a muscle

105
Q

What are myofibrils composed of?

A

Thick and thin filaments

106
Q

What are thick filaments composed of?

A

Protein myosin

107
Q

What are thin filaments composed of?

A

Protein actin

108
Q

What are troponin and tropomyosin?

A

Regulatory proteins

109
Q

How is muscle contraction described?

A

By the sliding filament model of contraction. Sliding of the thin filaments by the thick filaments. Sarcomeres, myofibrils, and muscle fibers shorten to produce movement.

110
Q

What triggers depolarization at the NMJ?

A

ACh is the neurotransmitter that binds at the neuromuscular junction (NMJ)

111
Q

In skeletal muscle, what does an action potential travel down?

A

Sarcolemma

112
Q

In skeletal muscle, an action potential causes the release of what from where?

A

Calcium from the sarcoplasmic reticulum

113
Q

What happens when the actin sites are exposed to calcium?

A

Activates the tropinin-tropomyosin complex which causes the tropomyosin to shift away from the sites. The cross bridging of myosin heads docking into actin-binding sites is followed by the “power stroke” - sliding of the thin filaments by thick filaments.

114
Q

What are power strokes powered by?

A

ATP

A&P (19 decks)

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