Chapter 10 Flashcards
Blood is important for what
Maintaining homeostasis
Blood brings and Carrie’s what
Brings oxygen and nutrients to cell, Carries away waste from cells
Blood is what kind of tissue
Connective
Blood is what percent of body weight
8%
Blood transports what to cells
Nutrients and other substances
What waste does blood filter out
Acids and drugs
Blood transports…
Hormones
PH regulation is between what
7.35 and 7.45
Substances maintain osmotic pressure to regulate?
Fluid in tissues
How many liters of blood is in men
5-6 liters
How many liters of blood in women
4-5 liters
Suspension
Cells in a fluid
Erythrocytes
Red blood cells
Leukocytes
White blood cells
Platelets (thrombocytes)
Cell fragments
Blood is made up of what
55% blood cells
45% cells
Buffy coat layer
Located between the two (white blood cells and platelets)
Hematocrit
Refers to percentage of volume of blood that is made up of cells
Polyathemia
High hemtocrit
Anemia
Low hematocrit
Alalmin
Most a funding in plasma
Important on maintaining osmotic pressure
Globulins
Alpha and beta globulins
Transports lipids and fat solvable vitamins
Gamma globulins
Antibodies
Fights infection
Fibrinogen
Necessary for blood clotting
Electrolytes
Salts like chloride, carbonate, phosphate, sodium, potassium, calcium, magnesium
Red blood cells are…
The most numerous
4.5-5 million per millimeter cubed of blood
Red blood cells are destroyed by
Liver or spleen
Mature cells are…
Anuclear
No nucleus
No mitochondria
Red blood cells contain
Hemoglobin
Binds to oxygen for transport
Oxyhemoglobin
Hemoglobin with oxygen
Bright red color
Deoxyhemoglobin
Hemoglobin without oxygen
Darker color
Carbon monoxide
Blocks hemoglobins ability to carry oxygen
Macrophages
In spleen and liver destroy worn out RBC
Heme
Contains iron which is recycled and billrubin which goes to liver
Globin
Broken into amino acids and recycled
Erythropoietin
Hormone from kidney that is released in response to low oxygen levels in blood
Producing RBC requires these three things
Protein
Vitamins B12 and folic acid to make DNA
iron (to make hemoglobin)
Anemia
Deficiency of red blood cells or red blood cells with low amount of hemoglobin
Lowers oxygen carrying capacity of blood
Hemorrhagic anemia
Blood loss
Iron deficiency anemia
Lack hemoglobin
Sickle cell anemia
Abnormal hemoglobin
Hemolytic anemia
RBC lysis
Type O blood
Given to any ABO type (universal donar)
Type AB
Blood can receive any ABO type (universal recipient)
Rh-positive
Blood has antigen
Rh negative
Blood lacks antigen
Cant give rh positive blood to a rh negative individual
Platelets
Smallest formed element
Not cells- no nuclei or DNA
fragments released from megakaryocytes
Lifespan of platelets
10 days
Hemostasis
The stoppage of bleeding
Prevents blood loss when blood vessel ruptures
Vasoconstriction
Contraction of smooth muscles in blood vessel wall
Platelet plug formation
Platelets adhere to surface of broken vessel forming plug
Blood coagulation
Formation of a blood clot
Requires fibrinogen and calcium
Serum
Plasma without fibrinogen and other clotting factors
Neutrophillis
Most numerous (58% of WBCs)
Increase in number in response to infection
Do phagocytosis
Eosinophils
Increase in number of allergic reactions
Help control inflammation
Basophils
Release histamine
Promotes inflammation dilates blood vessels
Release heparin inhibits blood clotting
Lymphocytes
2nd most numerous (34% WBCs)
Important in Im unity
May form plasma cells: produce antibodies for immunity
Monocytes
Largest of WBC
6% total of WBC
can form macrophages, large cells important in disposing of invaders and foreign material
Leucopenia
Low WBC count less than 5,000
Cause: radiation, shock, and chemotherapy
Also flu fever measles mumps or chicken pox
Leukocytosis
High WBC over 10,000
Cause: acute infections vigorous exercise great loss of body fluids dress and anesthesia
Leukemia
Several types of blood cancer
Physiology: uncontrolled proliferation of abnormal or immature wbcs in the bone marrow
Results in fewer normal wbc RBC and platelets
Caused by mutation of white blood cell causing it to divide uncontrollably