Chapter 09: Translation Flashcards

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0
Q

What are the three regions of the ribosome?

A

Peptidyl site (P-site), aminoacyl site (A-site), and exit site (E-site)

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1
Q

What are the three stages of translation?

A

Initiation, elongation, and termination

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2
Q

What binds to the stop codon of mRNA during translation?

A

Release factors (RF)

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3
Q

What is the first step of initiation of translation in prokaryotes?

A

Binding of 16S rRNA in small subunit to Shine-Dalgarno consensus sequence (RBS) in the mRNA

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4
Q

What are polyribosomes?

A

Groups of ribosomes all actively translating the same mRNA

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5
Q

What is monocystronic mRNA?

A

An RNA that directs synthesis of a single kind of polypeptide

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6
Q

What are operons?

A

Groups of bacterial genes that share a single promoter and produce polycistronic mRNAs

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7
Q

What domain has the Shine-Dalgarno sequence on mRNA?

A

Prokaryota

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8
Q

Define synonym.

A

Codons that specify for the same amino acid

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9
Q

Define degenerate.

A

One amino acid specified by multiple codons

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10
Q

What enzyme attaches amino acids to tRNA?

A

Aminoacyl-tRNA synthetase

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11
Q

Every tRNA ends with ________-3’ ________________.

A

CCA-3’ acceptor stem

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12
Q

Ribosomal subunits perform proof reading activities during translation. [T/F]

A

False; ribosomal subunits do not perform proof reading activities during translation.

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13
Q

The genetic code can be described as overlapping. [T/F]

A

False; the genetic code is non-overlapping and contiguous

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14
Q

Modified nucleotide imposing (I) can base pair to pyrimidines only. [T/F]

A

False; inosine can base pair with pyrimidines and purines.

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15
Q

The Shine-Dalgarno sequence is the translation promoter region found in prokaryotes. [T/F]

A

True.

16
Q

During translation initiation, the first tRNA enters at the peptidyl site. [T/F]

A

True.

17
Q

What in the ER aids the folding of protein molecules?

A

Chaperone molecules