Chapter 02: Transmission Genetics Flashcards

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0
Q

Males and females are affected in equal numbers. [Inheritance]

A

Autosomal dominant/recessive

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1
Q

Each individual who has the disease has at least one affected parent. [Inheritance]

A

Autosomal dominant

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2
Q

Either sex can transmit the disease. [Inheritance]

A

Autosomal dominant/recessive

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3
Q

If one parent is affected and the other is not, roughly half the offspring express the disease. [Inheritance]

A

Autosomal dominant

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4
Q

Two unaffected parents will not have any children with disease. [Inheritance]

A

Autosomal dominant

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5
Q

Two affected parents may produce unaffected children. [Inheritance]

A

Autosomal dominant

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6
Q

Individuals who have the disease are often born to parents who do not. [Inheritance]

A

Autosomal recessive

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7
Q

If only one parent has the disorder, the risk of passing it on depends on the genotype of the other parent. [Inheritance]

A

Autosomal recessive

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8
Q

If both parents have the disorder, all children will have the disorder. [Inheritance]

A

Autosomal recessive

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9
Q

If an affected child is born from unaffected parents, the risk to subsequent children is 1/4. [Inheritance]

A

Autosomal recessive

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10
Q

If the disease is rare in the population, unaffected parents of an affected child are more likely to be related to one another. [Inheritance]

A

Autosomal recessive

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11
Q

For the cross BBxBb, what are the expected genotype and phenotype ratios?

A

Genotype - 1:1:0

Phenotype - 1:0

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12
Q

What are the five features of Mendel’s experiments?

A

Controlled crosses, pure-breeding strains, single traits with dichotomous phenotypes, quantification of results, replicate- reciprocal- and test-crosses

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13
Q

Define replicate cross.

A

Repeating the same cross over and over

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14
Q

Define reciprocal cross.

A

Same genotypes are crossed, but sex of parents is switched

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15
Q

Define test cross.

A

Crossing an unknown genotype with an organism that’s homozygous recessive for the same trait

16
Q

What theory did Mendel reject?

A

Blending theory of inheritance

17
Q

What theory did Mendel support?

A

Theory of particulate inheritance

18
Q

What is the law of segregation (Mendel’s first law)?

A

The two alleles for each trait will separate during gamete formation, and they each have an equal chance (0.5) of inclusion; there is random unity during fertilization

19
Q

What is the law of independent assortment (Mendel’s second law)?

A

The segregation of alleles at one locus is independent of the segregation of alleles at a different locus

20
Q

The PAR is found on both the X and Y chromosome. [T/F]

A

True.

21
Q

What syndrome has the genotype 46XO?

A

Turner syndrome

22
Q

Define haploinsufficiency.

A

When two copies of the wild-type allele are needed to produce the wild-type phenotype