Chap. 10 - Dementia Flashcards

1
Q

Dementia - impaired cognition or impaired consciousness?

A

Impaired cognition

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2
Q

The most common type of dementia

A

Alzheimer’s type

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3
Q

The second-most common type of dementia

A

Vascular dementia

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4
Q

Vascular dementia is also known as…

A

Multi-infarct dementia

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5
Q

Development of dementia with HIV is a ___ sign and generally means life expectancy of ___ _____

A

Bad sign

Six months to live

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6
Q

Dementia due to HIV, like Huntington’s disease, is classified as a _____ dementia

A

Subcortical

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7
Q

Pick’s disease is also known as _____ dementia

A

Frontotemporal

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8
Q

Creutzfeldt-Jacob disease progresses _____ and is _____

A

Progresses quickly and is fatal

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9
Q

Huntington’s disease, like HIV dementia, is classified as a _____ dementia

A

Subcortical

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10
Q

Alzheimer’s comes on suddenly or gradually?

A

Gradual onset

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11
Q

Post-mortem hallmarks of Alzheimer’s are…

A

Amyloid deposits and neurofibrillary tangles

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12
Q

Vascular dementia results from…

A

CV disease

HTN

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13
Q

HIV dementia manifests by progressive _____ decline, _____ abnormalities, and _____ abnormalities.

A

Progressive cognitive decline
Motor abnormalities
Behavioral abnormalities

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14
Q

HIV dementia may co-occur with _____-_____ disorder, _____ _____ disorder, and _____ _____ disorder

A

Obsessive-compulsive disorder
Posttraumatic stress disorder
Generalized anxiety disorder

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15
Q

Protease inhibitors will _____ levels of Wellbutrin, most benzos, and SSRIs

A

Increase levels, causing toxicity

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16
Q

Protease inhibitors will _____ levels of Depakote and Ativan

A

Decrease levels, rendering standard doses subtherapeutic

17
Q

The early stages of Pick’s disease are marked by _____ and _____ changes, while the late stages are marked by _____ changes

A

Personality and behavior changes early

Cognitive changes late

18
Q

The Kluver-Bucy syndrome of Pick’s disease is marked by hyper-_____, hyper-_____, and _____.

A

Hypersexuality
Hyperorality
Placidity

19
Q

Creutzfeldt-Jacob disease, early on, looks like the ___.

20
Q

Later manifestations of C-J disease include _____, _____, and emotional _____.

A

Aphasia
Apraxia
Emotional lability

21
Q

Death from C-J disease happens in about __ months.

A

Six months

22
Q

Huntington’s disease is characterized by choreoathetoid movements, which means _____ _____.

A

Motor abnormalities

23
Q

Although the Huntington’s patient is stricken with choreoathetoid movements, their _____ remains intact until the late stages.

A

Cognition (memory, language, and insight)

24
Q

Lewy body disease presentation

A

Hallucinations
Parkinsonian features
EPS

25
Do NOT treat Lewy body with this drug class:
Antipsychotics
26
Dementia affects about __% of individuals aged 65-85, and about __% of individuals over 85
1.6% from 65-85 | 16-25% of those over 85
27
The most common dementia is
Alzheimer's
28
Screening recommendations
Screening is NOT recommended, as there is no treatment
29
Instruments for assessing level of impairment (3)
MMSE Short Portable Mental Status Questionnaire (SPMSQ) Blessed Dementia Rating Scale (BDRS)
30
Amaurosis fugax
Unilateral transient vision loss, described as "curtain over the eye"
31
Three A's of dementia
Aphasia Apraxia Agnosia
32
Two "down there" causes to rule out
UTI | Syphilis
33
Cognitive symptoms may be stabilized by NMDA Glutamate Receptor Antagonists like
Memantine (Namenda)
34
Cholinesterase inhibitors like _____ (_____) and _____ may help to treat symptoms and slow loss of function but are NOT effective in end-stage disease
Donepezil (aricept) and Rivastigmine
35
Psychosis and agitation in dementia should be treated with
Antipsychotics