Ch.23 Flashcards
What can slow down wound healing?
*Skin Infection
What is granular tissue?
Begins as new capillaries form and connective tissue fibroblasts multiply producing red translucent
- Fills space created by wound
- Shrinks, is converted to collagen covered by skin or mucous membrane
What is an abscess?
- localized pus surrounded by inflamed tissue
What is abscess made out of?
made out of pus: thick, yellowish fluid composed of living and dead leukocytes, tissue debris, and proteins
Abscess can be dangerous?
- Difficult to treat: no blood vessels; adjacent blood vessels often blocked by clots
– Lack of circulation may prevent antimicrobials from reaching infected site; pus may interfere with action
– Microbes stop multiplying, so most antimicrobial medications ineffective
– Abscesses must burst to body surface or be drained surgically
What is the most frequent genus of bacteria that causes wound infection?
Staphylococcus aureus
Why is it not surprising that Staphylococcus aureus causes most wound infections?
- Can commonly inhabit nostrils, skin
What is the causative agent of flesh-eating disease?
Group A Streptococcal
Streptococcus pyogenes.
What is the causative agent of tetanus and how does it appear under the microscope?
- Clostridium tetani
- Anaerobic, Gram-positive, rod-shaped; forms spherical endospore at one end of cell
How can lung damage occur in a person with tetanus?
from pneumonia or regurgitation of stomach contents
What is the causative agent of gas gangrene?
- Clostridium perfringens
How does Clostridium perfringens cause gas gangrene? What kinds of conditions are needed for growth?
- due to presence of dirt and dead tissue in wound, long delays before wound is treated
- mostly in neglected trauma wounds because agent requires anaerobic conditions for growth
What is gas gangrene treated and prevented?
- Prompt removal of all dead and infected tissue; perhaps amputation
- Antibiotics, perhaps hyperbaric oxygen treatment
- No available vaccine
- Prevention by prompt cleaning and debridement of dead tissue from wounds
What are the symptoms of cat scratch disease?
- Pus-filled pimple appears within a week
- Possible fever, malaise, headache; lymph nodes may be pus-filled, soft and enlarged
What is the causative agent of cat scratch disease?
- Bartonella henselae
- curved, Gram-negative rod
Do bites from small children typically cause disease?
- children’s mouths are not very strong
- Human bites can result in serious infections from normal mouth microbiota in blood or saliva
What is meant by synergistic infections?
occurs when two or more viruses or microbes infect the same cell or community
What is a fungal disease associated with gardening?
Sporotrichosis (“Rose Gardener’s Disease”)
How is Sporotrichosis (“Rose Gardener’s Disease”) spread?
Typically caused by soil fungi that enter via injuries
