Ch.22 Flashcards
What are 4 very important functions of the skin?
- Prevents entry of microbes
- Regulates body temperature
- Restricts fluid loss from tissues
- Senses environment
- Contains skin-associated lymphatic tissue (SALT)
- Role in function of immune system
What are the names of the different layers of the skin?
Skin composed of two layers
1. Epidermis: surface layer made from layers of flat cells
- Outermost are dead and filled with water-resistant keratin
- Constantly flake off and replaced from deeper layers
- Microbes are shed with flaking skin
2. Dermis: connective tissue
- Contains nerves, glands, blood and lymphatic vessels
3. Subcutaneous tissue: supportive; fat, blood vessels
What are 4 antimicrobial aspects of the skin?
- dryness
- saltiness
- acidic
- toxic
What is the most common causative agent of acne?
Cutibacterium (Propionibacterium) acnes
S. aureus produces Protein A. How does it interfere with the immune system?
Protein A inhibits phagocytosis
S. aureus produces coagulase. How does it interfere with the immune system?
Coagulase and clumping factor manipulate host’s blood clotting system allowing the organism to colonize soft tissues while avoiding the immune response
What is the causative agent of chickenpox?
Varicella-zoster virus (VZV) of Herpesviridae: enveloped, double- stranded DNA virus
What does the MMR vaccine protect against?
measles, mumps, rubella
What is the causative agent of warts?
Papillomaviruses (PV)
What word do we use to describe all diseases caused by fungi?
Mycoses are diseases caused by fungi
Skin invading molds are collectively called ___
dermatophytes
We covered the names of different skin fungal infections. What do we call infections of the feet, scalp, groin, beard and armpits?
- jock itch, athlete’s foot, ringworm
- caused by dermatophytes
