Ch.19- Blood Flashcards
What is found at the core of the hemoglobin?⭐️
Iron
Average life span of RBC circulating in the blood⭐️
120 days
What is stationary and can cause DVT(deep vein thrombosis)⭐️
Thrombocytes
What travels and can cause PE(pulmonary Embolism)⭐️
Embolus
How to tell if someone has jaundice⭐️
Yellow sclera
The 5 types of WBCs from Most abundant to Least Abundant(NLMEB)⭐️
Neutrophils, Lymphocytes, Monocytes, Eosinophils, Basophils
Which plasma protein is used to stabilize blood clots?⭐️
Fibrinogen
Active form of fibrinogen⭐️
Fibrin
Most abundant protein in PLASMA⭐️
Albumins
Mature erythrocytes do not have nucleus but have…
Hemoglobin
Globulins are immunoglobulins. What is another term for immunoglobulin⭐️
Antibodies
Albumins, alpha and beta globulins, and fibrinogens are produced by what⭐️
Liver
If we lack iron, will it effect oxygen?⭐️
Yes
What shape is a mature RBC?⭐️
Biconcave disc ♾️
Gamma globulins (immunoglobulins) are produced by…⭐️
White Blood Cells
What makes up the formed elements⭐️
RBC(erythrocytes), WBC(leukocytes), & Thrombocytes
T & B cells are made in…⭐️
The bone
The largest portion of plasma is..⭐️
Water
What is the term for the process of blood cell production⭐️
Hematopoiesis
What is the precursor cell to red blood cells⭐️
Proerythrocytes
What is the precursor cell to platelets (thrombocytes)⭐️
Megakaryocytes
What is the precursor cell to the 3 granulocytes⭐️
Myeloblasts
What is the precursor cell to monocytes⭐️
Monoblasts
What is the precursor cell to lymphocytes⭐️
Lymphoblasts
ToF: A mature red blood cell has no nucleus or organelles but is instead filled with hemoglobin⭐️
True
What is erythropoiesis⭐️
RBC production
Does fetal or adult Hb have a higher affinity for oxygen
Fetal Hb
Why do adult males have a higher Hematocrit(erythrocyte blood count) than adult females?⭐️
Testosterone and bc women have menstrual cycles
What gives urine its yellow-green color⭐️
Bilirubin
What are the 2 agranulocytes
Lymphocytes & Monocytes
What are the 3 granulocytes⭐️
Neutrophils, Eosinophils, &Basophils
What is the largest white blood cell⭐️
Monocyte
What is the smallest white blood cell
Lymphocyte
What is the order of recruitment towards infected cells in white blood cells?⭐️ (CMD)
chemotaxis, margination, then diapedesis
Monocytes move in the blood circulation but become what when stationary in injured tissues
Macrophages
Which WBC has 3-5 lobes and is a granulocyte⭐️
Neutrophils
Which WBC stains a pink/red color and is a granulocyte
Eosinophil
Which WBC stains a dark blue/black color and is a granulocyte?⭐️
Basophil
Which WBC has a nucleus that takes up most of the cell and is an agranulocyte?⭐️
Lymphocyte
Which WBC has a kidney-shaped nucleus and is an agranulocyte?
Monocytes
ToF: All 5 WBCs are bigger than a mature RBC⭐️
True
What is the most abundant WBC?
Neutrophils
ToF: Thrombocytes are fully functional cells⭐️
False
What is the order of hemostasis happening (arrest of bleeding)?
vascular spasm,
platelet plug formation,
then coagulation/blood clotting by fibrin
At what factor do the intrinsic and extrinsic paths of the clotting cascade meet?
Factor X
Which factors are vitamin K dependent
Factors II, VII, IX, and X
What does a deficiency in factor VIII result in
Hemophilia A
What does a deficiency in factor IX result in?
Hemophilia B
Adding what with inactive fibrogen results in active fibrin⭐️
Thrombin
Fibrin is made active for blood clotting, but what is made active for blood clot degradation
Plasmin
EC: In the clinical setting, what is a clot buster(tPA)⭐️
tissue plasminogen activator (tPA)
Surface antigens on red blood cells classify what
ABO blood types
What is another name for clump?⭐️
Agglutination
ToF: Clumps and clots are the same⭐️
False
T/F The blood type is dependent on the surface antigen that is present⭐️
True
What Type of blood does not have a surface antigen?⭐️
Type O
When Rh is present, the blood type is what (Rh being absent has opposite outcome)?⭐️
Negative
Blood type A has what surface antigen and plasma antibodies?⭐️
antigen A and anti B antibodies
Blood type B has what surface antigen and plasma antibodies⭐️
Antigen B & anti A antibodies
Blood type AB has what surface antigens and plasma antibodies⭐️
Antigens A and B and no antibodies
Blood type O has what surface antigen and plasma antibodies
No antigen & Anti A & B antibodies
Which blood type is the universal donor?
Type O
Which blood type is the universal receiver?⭐️
AB
When the mother’s Rh in her blood is not tested for a second pregnancy, what fatal outcome can happen to the baby? (EF)
Erythroblast-is fetalis
Determining someone’s Rh is most important in what case⭐️
Pregnancy
Which heart circuit follows this path: heart–>lungs–>heart⭐️
Pulmonary circuit
Which heart circuit follows this path: heart–>tissues of the body–>heart⭐️
Systemic circuit
Which heart circuit follow this path: heart–>blood vessels around the heart–>heart chamber⭐️
Coronary circuit
What powers the circuits to work?
Heart contractions
