Ch14 Pt3 Flashcards
Partial Pressure=
% concentration of gas x total pressure
PO2= .2093 (20.93%) x 760mmHg (sea level)
=159mmHg
If saturation drips below 60mmHg at PO2 and 40mmHg at muscle,
Would see decreased saturation and increased disassociation
4 Factors which increase O2 extraction at the muscle during exercise (internal respiration), (aVO2), (increase dissociation of oxyhemoglobin):
- Increase PO2 gradient
- Increase PCO2
- Decrease pH (increase acidity)
- Increase Tempurature (increases oxygen uptake in muscle)
What does Increasing the PO2 gradient do?
-increase pressure gradient (blood stream to muscle) from rest to exercise
-decrease % O2 saturation of hemoglobin
-increase O2 disassociation from hemoglobin and more O2 available for muscle
What does Increasing the PO2 gradient do?
-increase pressure gradient (blood stream to muscle) from rest to exercise
-decrease % O2 saturation of hemoglobin
-increase O2 disassociation from hemoglobin and more O2 available for muscle
- What does increasing the PCO2 gradient do?
-muscle gives off CO2 into blood, disassociating O2 from hemoglobin
-decrease %O2 saturation
-increase O2 extraction to muscle during exercise
What does a decrease in pH levels do?
-decrease % saturation of hemoglobin for PO2 (less carrying capacity)
-increased O2 extraction to muscle during exercise
What does increasing temperature do?
-decreased % saturation of hemoglobin for given PO2
-increased O2 extraction to muscle gives off
carrying Capacity of O2 affected by: (3)
- Increase Partial pressure (PO2)= increase carrrying capacity
- Increase temperature = decrease carrying capacity
- Decrease pH (high acid concentration)= decrease carrying capacity
What is exercise Induced Hypoxemia?
Condition found in endurance athletes which the amount of oxygen carried in arterial blood is severely reduced
-pulmonary system lags behind exxceptional adaptations in CV and MS
-comprises arterial O2 saturation and O2 carrying capacity
-less O2 delivered to muscle
Causes of Exercise Induced Hypoxemia
-inequality between ventilation and perfusion
-limitations in oxygen diffusion from RBCs -incomplete diffusion
Increase in PCO2 from rest to exercise:
Right shift of the oxyhemoglobin curve
Exercise induced Hypoxemia affects:
40-50% of highly trained athletes