Ch 9 Muscle Physiology Parts 1 & 2 Flashcards

1
Q

3 Muscle tissue types

A

Skeletal, Smooth, Cardiac

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2
Q

3 Myocyte structures

A

Sarcolemma = plasma membrane
Sarcoplasm = cytoplasm
Myoofibrils = Contractile structure of a cell

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3
Q

What are T-tubules

A

invaginations of sarcolemma

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4
Q

T-tubule function

A

Transfer of action potentials

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5
Q

What’s the triad

A

T-tubule between two terminal cisternae

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6
Q

What is terminal cisternae

A

Sacs adjacent to t-tubules

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7
Q

What is the sarcoplasmic reticulum

A

Internal membrane complex (smooth ER)

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8
Q

Two types of filaments

A

thick and thin

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9
Q

Thick filament is called what

A

Myosin

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10
Q

Thin filament is called what

A

Actin

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11
Q

3 parts of thin filament structure

A

Troponin, Tropomyosin, Actin

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12
Q

What does Nebulin do

A

Plays a role in filament assembly

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13
Q

What does troponin do

A

Regulates contraction

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14
Q

What does tropomyosin do

A

Regulates contraction

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15
Q

What is myosin composed of

A

two large polypeptide heavy chains

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16
Q

Globular heads do what

A

Form cross bridges: for contact with thin filament

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17
Q

What are sarcomeres

A

Functional units of myocytes

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18
Q

What are Z discs

A

Proteins that anchor thin filaments

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19
Q

What are alpha motor neurons

A

Neurons whose axons innervate skeletal myocytes

20
Q

Neuromuscular junction cell bodies are located in…

A

The brainstem and spinal cord

21
Q

Are all motor neuron axons myelinated?

A

Yes

22
Q

What is the axon terminal

A

Synaptic vesicles and active zones

23
Q

What is the synaptic cleft?

A

Space between axon and sarcolemma

24
Q

What is the motor end plate

A

ACH receptors and junctional folds

25
Q

Ca 2+ binds to…

A

Troponin

26
Q

Troponin and Ca2+ binding causes what

A

Sliding Filament mechanism

27
Q

Acetylcholinesterase breaks down what

A

ACH

28
Q

Ca2+-ATPase pumps do what

A

return Ca2+ ions to the SR by active transport

29
Q

Tropomyosin is held in blocking position by…

A

Troponin

30
Q

Name the troponin sub units

A

Troponin I (inhibitory)
Troponin T (tropomyosin binding)
Troponin C (calcium binding)

31
Q

Force generations produces what for a muscle fiber

A

Shortening

32
Q

3 types of Muscular Distrophy

A

Duchenne
Becker
Limb-girdle

33
Q

Muscle contraction is based on what two factors

A

Force and Length

34
Q

Describe muscle tension

A

force from muscle on an object

35
Q

Describe muscle load

A

Force by an object on a muscle

36
Q

3 types of muscle contraction

A

Concentric
Eccentric
Isometric

37
Q

Summation is…

A

increase in muscle tension from successive action potentials occurring during mechanical activity

38
Q

Tetanic contraction is

A

A maintained contraction in response to repetitive stimulation

39
Q

Muscle fatigue occurs when…

A

A skeletal myocyte is repeatedly stimulated

40
Q

Onset of fatigue depends on

A

type of active myocyte (fast vs slow twitch)
Intensity
Duration

41
Q

What is botulism

A

Limp baby
Caused neurotoxin SNARE protein

42
Q

Name difference between glycolytic and oxidative fibers

A

glycolytic is fast twitch
Oxidative is slow twitch

43
Q

Oxidative fibers contain…

A

myoglobin
also called red muscle fibers

44
Q

Glycolytic Fibers lack…

A

Myoglobin
Referred to as white muscle fibers

45
Q

Three fiber types

A

Slow oxidative
Fast oxidative
Fast glycolytic