Ch 9 Muscle Physiology Parts 1 & 2 Flashcards

1
Q

3 Muscle tissue types

A

Skeletal, Smooth, Cardiac

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2
Q

3 Myocyte structures

A

Sarcolemma = plasma membrane
Sarcoplasm = cytoplasm
Myoofibrils = Contractile structure of a cell

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3
Q

What are T-tubules

A

invaginations of sarcolemma

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4
Q

T-tubule function

A

Transfer of action potentials

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5
Q

What’s the triad

A

T-tubule between two terminal cisternae

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6
Q

What is terminal cisternae

A

Sacs adjacent to t-tubules

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7
Q

What is the sarcoplasmic reticulum

A

Internal membrane complex (smooth ER)

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8
Q

Two types of filaments

A

thick and thin

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9
Q

Thick filament is called what

A

Myosin

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10
Q

Thin filament is called what

A

Actin

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11
Q

3 parts of thin filament structure

A

Troponin, Tropomyosin, Actin

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12
Q

What does Nebulin do

A

Plays a role in filament assembly

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13
Q

What does troponin do

A

Regulates contraction

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14
Q

What does tropomyosin do

A

Regulates contraction

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15
Q

What is myosin composed of

A

two large polypeptide heavy chains

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16
Q

Globular heads do what

A

Form cross bridges: for contact with thin filament

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17
Q

What are sarcomeres

A

Functional units of myocytes

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18
Q

What are Z discs

A

Proteins that anchor thin filaments

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19
Q

What are alpha motor neurons

A

Neurons whose axons innervate skeletal myocytes

20
Q

Neuromuscular junction cell bodies are located in…

A

The brainstem and spinal cord

21
Q

Are all motor neuron axons myelinated?

22
Q

What is the axon terminal

A

Synaptic vesicles and active zones

23
Q

What is the synaptic cleft?

A

Space between axon and sarcolemma

24
Q

What is the motor end plate

A

ACH receptors and junctional folds

25
Ca 2+ binds to...
Troponin
26
Troponin and Ca2+ binding causes what
Sliding Filament mechanism
27
Acetylcholinesterase breaks down what
ACH
28
Ca2+-ATPase pumps do what
return Ca2+ ions to the SR by active transport
29
Tropomyosin is held in blocking position by...
Troponin
30
Name the troponin sub units
Troponin I (inhibitory) Troponin T (tropomyosin binding) Troponin C (calcium binding)
31
Force generations produces what for a muscle fiber
Shortening
32
3 types of Muscular Distrophy
Duchenne Becker Limb-girdle
33
Muscle contraction is based on what two factors
Force and Length
34
Describe muscle tension
force from muscle on an object
35
Describe muscle load
Force by an object on a muscle
36
3 types of muscle contraction
Concentric Eccentric Isometric
37
Summation is...
increase in muscle tension from successive action potentials occurring during mechanical activity
38
Tetanic contraction is
A maintained contraction in response to repetitive stimulation
39
Muscle fatigue occurs when...
A skeletal myocyte is repeatedly stimulated
40
Onset of fatigue depends on
type of active myocyte (fast vs slow twitch) Intensity Duration
41
What is botulism
Limp baby Caused neurotoxin SNARE protein
42
Name difference between glycolytic and oxidative fibers
glycolytic is fast twitch Oxidative is slow twitch
43
Oxidative fibers contain...
myoglobin also called red muscle fibers
44
Glycolytic Fibers lack...
Myoglobin Referred to as white muscle fibers
45
Three fiber types
Slow oxidative Fast oxidative Fast glycolytic