Ch 15 Digestive Part 1 and 2 Flashcards

1
Q

Metabolism

A

total of chemical reactions occuring at the same time

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2
Q

catabolism

A

breakdown of organic molecules by the cells

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3
Q

anabolism

A

synthesis of organic molecules by cells

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4
Q

Chemical reactions

A
  • breaking chemical bonds in reactant molecules
  • breakdown and synthesis of organic molecules is accomplished through chemical reactions
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5
Q

what type of protein is more rapidly degrades

A

denatured (unfolded)

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6
Q

what targets proteins for degradation

A

ubiquitin (small peptide)

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7
Q

what do ubiquitins do

A

directs the protein a proteasome which unfolds the proteins and breaks it down into small peptides

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8
Q

describe reactant concentration

A

greater concentrations = faster reaction rate

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9
Q

describe activation energy

A

greater activation energy = slower reaction rate

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10
Q

describe temperature in reaction rates

A

higher temp = faster reaction rate

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11
Q

describe a catalyst in reaction rates

A

speeds up reaction rate

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12
Q

What are enzymes

A

protein molecules that act as a protein catalyst

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13
Q

enzyme mediated reactions

A

start when enzyme makes contact with reactants (substrates)

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14
Q

enzyme substrate complex

A

substrate binds to enzyme which then breaks down to release an enzyme

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15
Q

2 enzyme models

A
  • lock-and-key
  • induced-fit
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16
Q

what are the three enzyme mediated reaction regulations

A
  • substrate concentration
  • enzyme concentration
  • enzyme activity
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17
Q

allosteric modulation

A

requires phosphate enzyme
(think allosteric phosphate)

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18
Q

covalent modulation

A

requires a kinase enzyme
(think covalent kinase)

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19
Q

Main 4 processes of GI tract

A

Absorption
Secretion
Digestion
Motility

20
Q

5 stages of food processing

A

Ingestion - Mouth
Digestion - Stomach
Absorption - Small Intestine
Compaction - Large intestine
Defecation - Anus

21
Q

Mechanical digestion

A

physical breakdown of food

22
Q

Chemical digestion

A

hydrolysis reactions to break macromolecules into monomers

23
Q

Swallowing Center location

A

Located in the medulla oblongata

24
Q

3 salivary glands

A

parotid
sublingual
submandibular

25
3 swallowing phases
oral -> forms food to bolus pharyngeal -> block oral cavity, push bolus to esophagus esophageal -> peristalsis, push bolus down into stomach
26
3 phases of GI control
cephalic phase gastric phase Intestinal phase
27
cephalic phase
stomach being controlled by brain
28
gastric phase
stomach controlling itself
29
intestinal phase
stomach being controlled by small intestine
30
4 parts of anatomy of stomach
cardial part fundus body antrum
31
Types of cells in gastric glands
mucous cells - secrete mucus Parietal cells - secrete HCL, intrinsic factor, and ghrelin ECL cells - secrete histamine, G (gastrin) cells, and D (somatostatin) cells Chief Cells - most numerous, secrete gastric lipase and pepsinogen
32
HCL- actives...
Pepsin and lingual lipase
33
Where is proton pump
in lumen of parietal cell
34
4 neurohumoral inputs that regulate acid secretion
Gastrin Histamine Acetylcholine Somatostatin
35
What is intrinsic factor
a glycoprotein secreted by parietal cells
36
Pepsinogen is...
inactive enzyme secreted by chief cells
37
HCL changes the conformation of..
pepsinogen to pepsin
38
Autocatalytic effect
converting more pepsinogen into pepsin
39
Pepsin digests dietary proteins
into shorter peptides
40
Where is protein digestion completed
In the small intestine
41
What does pepsin break
proteins
42
tight junctions
between epithelial cells prevent gastric juice from seeping between them
43
Common locations of gastric & duodenal ulcers
body or antral region duodenum
44
intestinal motility three functions
mix chyme churn chyme for digestion and absorption Move residue toward large intestine
45
what does chemical digestion in the duodenum
pancreatic enzymes
46
location of most nutrient absorption in large intestine
jejunum