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Pathology > Ch 7 > Flashcards

Ch 7 Flashcards

1
Q

HHV 1

A

Herpes simplex virus 1
Best adapted to above the waist locations (saliva/perioral)
Younger = acute herpetic gingivostomatitis
18+ = pharyngotonsillitis

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2
Q

HHV 2

A

Herpes simplex virus 2
Best adapted to below the waist locations (sexual)
Latency; trigeminal ganglion

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3
Q

HHV 3

A

Varicella Zoster virus (VZV)
Primary; chickenpox
Reocurrance; Herpes zoster (shingles)
Latency; dorsal spinal ganglia

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4
Q

HHV 4

A 
Epstein-Barr virus (EBV)
Infectious mononucleosis (kissing disease)(intimate contact)
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5
Q

HHV 5

A

Cytomegalovirus (CMV)
Resides: salivary gland cells, endothelium, macro and lymphocytes.
common in AIDS patients.
Histology: owl eye cell

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6
Q

HHV 8

A

Kaposi’s sarcoma herpesvirus (KSHV)

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7
Q

What are less common presentations of HHV 1

A

Herpetic whitlow
Herpes gladiatorum/scrumpox
Herpes barbae

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8
Q

What is the leading infectious cause of blindness in the US

A

HHV 1

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9
Q

What is the primary Tx for HSV

A

Acyclovir

Penciclovir

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10
Q

Hutchinson sign

A

HHV 3
If the tip of the nose is involved, it is a sign ocular infection might occur and referral to ophthalmologist is mandatory.

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11
Q

What is Ramsay Hunt syndrome

A

HHV 3
o Cutaneous lesions of the external auditory canal
o Involvement of ipsilateral face and auditory nerves
o Facial paralysis
o Hearing deficits
o Vertigo

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12
Q

How is HHV 4 diagnosed

A

Presence of Paul-Bunell heterophil antibodies

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13
Q

Enteroviruses are classified into what 3 categories

A

Echoviruses
Coxsackieviruses
Poliovirus

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14
Q

What are three infections caused by the Coxsackieviruses

A

Herpangina
Hand-foot-mouth disease
Acute lymphonodular pharyngitis

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15
Q

What is the major path of transmission for enteroviruses

A

Fecal-oral route

Acute phase; saliva/resp droplets

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16
Q

What is herpangina

A

skin rash

oral lesions; 2-6, 3 mm (soft palate, tonsillar pillars)

17
Q

What is hand-foot-and-mouth disease

A

Skin rash; erythematous macules with central vesicles.

Oral lesions;

18
Q

What type of virus is Rubeola/Measles caused by

A

Paramyxovirus

19
Q

What does nine-day measles mean

A

Rubeola; 3 stages with 3 days

20
Q

What is the first stage of rubeola/measles

A 
3c + fever
Coryza
Cough
Conjunctivitis
KOPLIK'S SPOTS; mucosal erythema with numerous small blue-white macules.
21
Q

What is the second stage of rubeola/measles

A

o Fever continues
o Koplik’s spots fade
o Maculopapular & erythematous (morbilliform) rash begins
• Face first
• Downward spread from trunk  extremities
• Blanches on pressure

22
Q

What is the third stage of rubeola/measles

A

Fever ends
rash fades in downward progression
replaced by brown pigmentary staining

23
Q

What virus is rubella/german measles caused by

A

togavirus

24
Q

What is rubella’s greatest importance

A

Congenital rubella syndrome; capacity to induce birth defects

25
Q

Rubella/german measles is know as the ___ day measles

A

3 day

26
Q

what is the most common complaint of rubella

A

arthritis

27
Q

What oral lesion is associated with rubella

A

Forchheimer’s sign; 20%, small discrete dark papules on palate.

28
Q

What is rubellas triad

A

Deafness 80%
Heart disease
Cataracts

29
Q

What is another name for Mumps

A

epidemic parotitis

30
Q

What is Mumps best know site of involvement

A

salivary glands (discomfort and swelling)

31
Q

What kind of disease is Mumps

A

disease of exocrine glands (edema and lymphocytic infiltration)

32
Q

What are the three most common routes of transmission fro AIDS

A

Sexual contact
Parenteral exposure to blood
Mother to fetus

33
Q

What cell is targeted in AIDS

A

CD4+ helper T lymphocyte

34
Q

What are the most common oral manifestations associated with AIDS

A 
Candidiasis
Hairy leukoplakia (EBV)
Kaposis's sarcoma 
Non-Hodgkin's lymphoma
Periodontal disease
35
Q

What is the Rx for AIDS/HIV pts

A

Clotrimazole

fluconazole

36
Q

What is Kaposi’s sarcoma

A

Multifocal neoplasm of vascular endothelial cell origin

37
Q

What sites are most commonly affected by KS

A

Hard palate
Gingiva
Tongue
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Pathology (17 decks)

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