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Pathology > Ch 14 > Flashcards

Ch 14 Flashcards

1
Q

What are the characteristics of benign bone neoplasia

A 
Asymptomatic
slow growth and by expansion
displaces teeth 
expands cortex
symmetrical 
does not metastasize
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2
Q

What are the characteristics of malignant bone neoplasia

A 
irregular borders 
noncorticated
asymmetrical
teeth floating in space 
capable of metastasis
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3
Q

Osteogenesis imperfecta is a defect in type___ collagen

A

I

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4
Q

What is the most common type of inherited bone diseases

A

osteogenesis imperfecta

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5
Q

What are the sx of osteogenesis imperfecta

A 
Bone fragility
blu sclera 
altered teeth
Hearing loss 
long bone and spine deformities 
Joint hyperextesibility
Osteopinia; low bone density
bowing 
wormian bones is skull
premature pulpal obliteration
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6
Q

What is the most common type of osteogenesis imperfecta

A

type I

Mildest, blue sclera through out life

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7
Q

What is the most severe form of osteogenesis imperfecta

A

Type III

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8
Q

What is the cause of Osteopetrosis/marble bone disease

A

marked increase in bone density due to a defect in remodeling caused by failure of normal osteoclast function

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9
Q

What is malignant osteoporosis

A

osteopetrosis discovered at birth

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10
Q

What are the sx of malignant osteoporosis

A 
maroow failure 
frequent fractures 
Cranial nerve compression 
delayed tooth eruption
Increased in skeletal density (radiopaque); roots hard to see.
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11
Q

What is the Tx for osteopetrosis infantile/malignant

A

Bone marrow transplant. 50% survive

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12
Q

What is another name for adult osteopetrosis

A

benign
less severe
long term survival

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13
Q

What is cleidocranial dysplacia

A

characterized by Dental and clavicle abnormalities.

clavicles missing or with varying degrees of hypoplasia

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14
Q

What are the sx of cleidocranial dysplacia

A

NUMEROUS UNERUPTED PERMANTENT AND SUPERNUMERARY TEETH.
short stature with big head
pronounced frontal bossing and hypertelorism
prolonged retention of deciduous teeth with delay/failure of eruption of permanent teeth.

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15
Q

what is osteoporotic marrow defect

A

area of hematopoietic marrow that produces radiolucency.
Might be confused with intraoseous neoplasm. incisional biopsy is necessary for dx.
75% in adult woman, posterior mandible

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16
Q

What are the characteristics of idiopathic osteosclerosis

A 
virgin tooth, mostly in mandible
Small filling
Normal pulp
asymptomatic 
no cortical expansion,
RADIOPAQUE
17
Q

What is conducing osteitis associated with

A

infections

18
Q

what is focal cemento-osseous displace associated with

A

radiolucent rim

19
Q

What is cementoblastoma associated with

A

it will be fused to the tooth

20
Q

What is paget’s disease of bone

A

abnormal resorption and deposition of bone resulting in distortion and weakening of affected bones
M>F
Bone pain
Might result in enlargement of skulls circumference and middle 1/3 of face leading to leontiasis ossea.
Patients might complain that denture no longer fits or increased space bn teeth.
X-ray= cotton roll appearance
High elevations in serum alkaline phosphatase levels with NORMAL calcium and phosphorus levels.
Possible development of osteosarcoma

21
Q

What nonneoplastic lesion is common in the anterior jaw and crosses the midline

A

Central Giant Cell Granuloma

22
Q

What is radiographically seen in cherubism

A

bilateral radiolucency in a young person

23
Q

What is a traumatic bone cyst

A

Benign empty or fluid filled cavity within bone; not lined with epithelium

24
Q

Radiographically what does domelike projections that scallop bn roots suggest

A

traumatic bone cyst

25
Q

What has the appearance of a blood soaked sponge or

blow out, ballooning distention of the contour of the affected bone.

A

Aneurysmal bone cyst

26
Q

What are fiber-osseous lesions

A

processes characterized by replacement of normal bone by fibrous tissue containing a mineralized product

27
Q

What are BFOLS

A

benign fibro-osseous lesions

28
Q

What are four examples of BFOLS

A

Fibrous dysplacia
Cemento-osseous dysplacia; focal, periapical, florid
Ossifying fibroma

29
Q

What does ground glass appearance on radiographs indicate

A

fibrous dysplacia

30
Q

What is a condition resulting from a post zygotic mutations

A

Fibrous dysplacia

Pathology (17 decks)

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