Ch. 6 Bones And Skeletal Tissues Flashcards

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1
Q

Bone nourishment

A
Blood vessel ->
Perforating canal ->
Central canal ->
Canaliculi. ->
Osteocyte.
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2
Q

Practice question

why does a surgeon order an X-Ray in a hand if a girl will have jaw surgery.

A

Hard to see if the patient is still growing so they need an accessible area to x-Ray and the hands is the easiest.
Epiphysis epiphyseal line and plate

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3
Q

Composition of bones

A

Bones

Joints with cartlidge, tendons, and ligaments

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4
Q

Cartilages

A

Hyaline cartlidge: provides firm support with some flexibility

  • Articular cartlidges cover the ends of bones at movable joints
  • Costal cartlidges connect ribs to the sternum (breastbone)
  • Respiratory test, voice box and nasal areas.

Elastic cartlidge:stretch flexibility, external ear and epiglottis (and flap covering larynx

Fibrocartlidge: Strength from collagen fibers but cushioning ability also found at sites subjected to heavy pressure and stretch (pubic symphysis). Pad like cartlidges of the knee (menisci). The discs between vertebrae (intervertebral discs)

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5
Q

Functions of Bones

A
Support
Protection 
Movement 
Mineral storage
Triglyceride (fat) storage
Blood formation
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6
Q

Classification of Bones: by shape not size

A

Long bones:elongated with shaft + two ends (finger, femurs)
Short bones: roughly cube shaped (ankle and wrist bones)
Flat bones: sternum, scapulae, ribs, most skull bones
Irregular bones: vertebrae, hip bones

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7
Q

Types of Bone Tissue

A

Compact: smooth and solid appearance
Spongy: Honeycomb, sponge like.

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8
Q

Gross Anatomy of Bones (naked eye)

A

Bone Markings
Structure of a typical Long Bone
Structure of short, irregular bones, and flat bones

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9
Q

Gross anatomy of Bone Markings

A

Projections (bulges): heads, trochanter psych, spines, etc.

Depressions and openings: Fossa, sinuses, foramina, grooves

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10
Q

Gross anatomy of Structure of a typical long bone

A

Diaphysis (shaft): forms longitudinal axis, medullary cavity filled with yellow marrow.

Epiphysis: (expanded end area): Epiphyseal line and plate.Red marrow produces red blood cells. Articular cartlidge.

Blood vessels: high vascularized

Membranes:
Periosteum (outside):outer double layered membrane
-Sharpey’s (perforating) fibers secures periosteum to underlying bone. More concentrated (dense) at tendon and ligament attachment.

     Endiosteum (inside): delicate, internal C.T. Membrane that lines all internal passageways.
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11
Q

Gross anatomy of the structure of short, irregular and flat bones

A

Stuffed sandwich with thin plates of periosteum-covered compact bone on the outside and endosteum- covered spongy bone within

Not cylindrical, so no shaft or epiphyses.
Contains bone marrow between trabeculae but no marrow cavity.

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12
Q

Microscopic anatomy of bone

A

Bone consists of extracellular matrix secreted by bone cells
Bone cells are entrapped within the matrix; responsible for maintains and remodeling.
Bones cells called:
Osteoblasts
Osteocytes
Osteoclasts

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13
Q

Osteoblasts

A

Makes bones
Bone forming cells, build up matrix called ossification or osteogenesis
Synthesize collagen
Accumulate calcium and phosphate
Appositional growth: osteoblasts of the inner periosteum add a new layer to the preexisting bone

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14
Q

Osteocytes

A

Mature bone cells that function to maintain the existing matrix. Osteoblasts trapped in the new matrix now called osteocytes.

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15
Q

Osteoclasts

A

Bone destroying cells
Responsible for the breakdown and reabsorption of bone matrix
Secrete H+ acid and enzymes to breakdown mineralized bone matrix
Calcium and phosphorus are freed

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16
Q

Microscopic anatomy of Compact Bone

A

Each unit is called an osteon.

Concentric lamella 
Central canal
Perforating canals
Canaliculi
Lacuna
Cell types: Osteoblasts, osteocytes, osteoclasts 
Circumferential lamellae
17
Q

Microscopic anatomy of spongy bone

A

Less dense than compact bone; lighter in weight but still strong
Consists of interconnecting plates called trabeculae with spaces in between.

18
Q

Chemical composition of bone matrix

A

Functional anatomy:
Flexibility + Strength
(Collagen). (Mineral salts, calcium- phosphate crystal)

19
Q

Bone Development (ossification)

A

Prior to week 8 during embryonic development, entire human skeleton is constructed of fibrous membranes and hyaline cartlidge.

2 types of bone growth

20
Q

Bone development : Intramembraneous

A

Intramembraneous ossification
In the matrix of the bone ossification centers develop within a fibrous membrane

Occurs in flat bones of the cranium (frontal, parietal, occipital, temporal) and clavicles -collarbones.

Remnants of Intramembraneous bone growth…fontanels.

Bone can be remodeled.

21
Q

Bone development: Endochondral ossification

A

Model for long bone growth and occurs in most bones inferior to skull.

Uses hyaline cartlidge “bones” as pattern for bone construction.

Osteocytes replace chondrocytes and the cartlidge matrix changes to the bone.

Makes Endochondral more complex as hyaline cartlidge must be broken down as ossification proceeds.

Active growth areas of cartlidge remain in the epiphyses forming Epiphyseal plate through adolescence.

Chondrocytes divide quickly, pushing the epiphyses away from the diaphysis, causing entire long bone to lengthen.

Medullary cavity also lengths, Epiphyseal plate maintains constant thickness.

Epiphyseal plate calcifies to form Epiphyseal line at 18 years female, 21 years male.

22
Q

Factors affecting bone growth

A

Nutrition and Hormones
Vitamin D: Rickets in childhood, demineralized bone, formative deformities

Calcium: Absorption is Vit. D dependent

Vitamin C: needed for collagen synthesis, scurvy, wound healing impaired, loose teeth.

Hormones: Secreted by pituitary gland

  • growth hormone (too much/ too little) tall or short
  • thyroid hormone
  • sex hormones: testosterone prolongs growth at Epiphyseal plates.
23
Q

Bone remodeling

A

Consists of bone deposits and bone resorption (removal)

A healthy bone is a “Stresses bone”

24
Q

Repair of Fractures

A
  • Nondisplaced / displaced: aligned ends?
  • Complete/ incomplete: break through?
  • Linear / transverse: what plane its on?
  • Open (compound) / Closed (simple): penetrates skin?

Treated by reduction (realignment of the bone)
Types:
-Comminuted: chunks
-Compression: crushed
-Depressed: Indent
-Impacted:
-Spiral: twisting
- Greenstick: incomplete break in kids softer matrix
*-Epiphysial fracture: plate: that is still cartlidge to sift in kids

Repair:

 - hematoma is formed.
 - Break is splintered by fibrocartlidge
 - Fibrocartlidge callus is replaced by bony callus
 - bony callus is remodeled
25
Q

Effects of aging

A
  1. Highest bone mass around 30.
    Higher in makes due to testosterone, and blacks and Hispanic
  2. Bones become brittle
    Collagen synthesized is less flexible, osteoblasts slowdown and deposit less mineral matrix, women susceptible in demineralization.
  3. Osteoporosis: results for rate of resorption being faster than of new bone formation, estrogen helps lessen osteoclast activity, as estrogen levels drop after menopause some women experience rapid demineralization, can loose up to 50% bone mass.

Other causes include reduction of dietary calcium and overproduction of PTH overactive osteoclasts

Treatment: weight bearing exercises, V-D, calcium supplements, drugs aimed at slowing osteoclasts (Fosamax, HRT)

Prevention: Increase Ca while young and still increasing their density, drink fluoridated water, weight excercise.

26
Q

Calcium Homeostasis in the Blood

A
  1. Ionic calcium is necessary for physiological processes such as nerve cell communication, muscle contraction, blood coagulation, and cell division.
  2. …very tightly controlled by the body within 10% of normal
    • increase by 30% will cause nervous and muscle cells to become unresponsive
    • decrease by 35% will cause overexcited neurons and convulsions
  3. Homeostatic balance of calcium: primarily controlled by parathyroid hormone (PTH) which is produced by the parathyroid glands.

See page 63 lesson graph

27
Q

Interstitial

A

Grow in length

28
Q

Appositional

A

Grow in width

29
Q

Epiphysis plate

A

Still growing

30
Q

Epiphysis line

A

Done growing

31
Q

Endochondrial ossification

A

Epiphysis bone. ——————
——————
——————
Epiphysis plate 00000000000
0000000000
Diaphysis bone. ——————
——————-
00000000000
00000000000
Epiphysis bone. ———————
———————-