Ch. 4 Blood Gas Flashcards
every decrease in 7 C= ? metabolic
decrease 50%
cold temperatures = ? solubility
increase solubility into solution
Celcius =
C= (F -32) x 5/9
Farenheit =
F= (C x 9/5) +32
Hemoglobin-O2 Dissociation Curve Shifts (LvsR)
Left Shift= higher affinity (lungs) Right Shift= lower affinity (O2 transfer in tissue) - high CO2, low pH - high temp - high 2,3 DPG
What is P50
P50 is the PO2 that gives you 50% hemoglobin saturation
- normal is 27 mmHg
- high P50= low affinity
- low P50= high affinity
1 gram fully saturated Hgb= ? ml O2
1.34 ml O2
O2 Capacity
= 1.34 x Hgb + (.003 x pO2)
O2 Content
= 1.34 x (Hgb x decimal saturation) + (.003 x pO2)
O2 Saturation
= O2 content/O2 capacity
O2 Consumption
= (aO2 - vO2 content) x L/min x 10
O2 Transfer
= [(A-V decimal sat) x 1.34 x Hgb x ml/min] / 100
pCO2 increase by 20 mmHg= what to pH
- decrease by 10 mmHg= what to pH
- drop .1 pH
- increase .1 pH
Respiratory Quotient
CO2 produced / O2 consumed
4:5
3 ways CO2 is transported
7% dissolved
23% Hgb
70% bicarb (CO2+H2O= H2CO3= H + HCO3-)
— chloride shift!= Cl-into cell, HCO3 out