Ch. 31 MOA

Question 1

Hyposecretion of thyriod horomone during youth. Results in a low metabolic rate, retarded growth and sexual development, and possible retardation.

Answer 1

Cretinism

Question 2

Hyposecretion of TH during adulthood. Decreases metabolic rate, loss of mental and physical stamina, weight gain, loss of hair, firm edema, and jaundice.

Answer 2

Myxedema

Question 3

An enlargment of the thyroid gland as a result of over stimulation of the thyroid glad.

Answer 3

Goiter

Question 4

A term that means ‘normal thyroid horomones.’

Answer 4

euthyroid

Question 5

Prefered drug for Tx of hypothyroidism because its content is standardized and therefore has a more predictable effect.

Answer 5

levothyroxine

Question 6

Most severe adverse effect of thyroid replacement medications

Answer 6

cardiac dsyrhythmias

Question 7

S/S: tachycardia, palpitations, angina, hypertension, insomnia, tremors, headache, anxiety, nausea, diarrhea, menstrual irregularities, weight loss, appetite changes, sweating, and heat intolerance

Answer 7

thyroid drugs adverse effects and also S/S of hyperthyroidism

Question 8

Inhibit the converstion of iodine into T3 and T4. May cause liver* and bone marrow toxicity

Answer 8

methimazole
propylthiouracil*

(*especially likely to cause liver toxicity)