Ch. 29 MAO

Question 0

First-line drug therapy for hypercholesterolemia. Reduce LDL levels and triglycerides, and increase HDL levels.

Answer 0

HMG-CoA Reductase Inhibitors

Question 1

Lower the rate of cholesterol production by inhibiting the enzyme that is used by the liver to produce cholesterol. Recommended to be taken in the evening.

Answer 1

HMG-CoA Reductase Inhibitors

Question 2

Adverse reactions include: myopathy possibly leading to rhabdomyolysis, and elevations in liver enzymes.

Answer 2

HMG-CoA Reductase Inhibitor

Question 3

____ should be monitored while a PT is taking HMG-CoA Reductase Inhibitors.

Answer 3

CPK

Question 4

Prevent resorption of bile acids from small intestine. Bile acids are necessary for absorption of cholesterol.

Answer 4

bile acid sequestrants

Question 5

Inhibits the absorption of cholesterol from the small intestine.

Answer 5

ezetimibe

Question 6

Believed to activate lipase. Suppresses the release of free fatty acid from adipose tissue, inhibits synthesis of triglycerides and increases secretion of cholesterol in the bile.

Answer 6

Fibric Acid Derivatives “fibrates”

Question 7

Thought to increase the activity of lipase, which breaks down lipids. Also decreases the metabolism of cholesterol and triglycerides.

Answer 7

niacin