Ch. 28 MOA

Question 0

Inhibit resorption of water sodium and chloride in the distal convoluted tubules. Potassium is excreted to a lesser extent. This medication also directly dilates arterials and therefore decreased peripheral resistance and decrease BP.

Answer 0

Thiazide and Thiazide-like Diuretics

Question 1

Work in collecting ducts and distal convoluted tubules. Competitively bind to and block aldosterone receptors and therefore block the resorption of sodium and water.

Answer 1

K-Sparing Diuretics

Question 2

Pull water into the renal tubules from the surrounding tissues. Inhibits tubular resorption of water and solutes and therefore rapid diuresis results. Must be given IV.

Answer 2

Osmotic Diuretic

Question 3

Reduce the H+ ion concentration in renal tubules, and results in increased excretion of bicarbonate, Na+, H2O, and K.

Answer 3

Carbonic Anhydrase Inhibitors

Question 4

Act directly on the ascending loop of Henle to inhibit sodium and chloride resorption. Also increase renal prostaglandins and therefore dilation of blood vessels and decreased peripheral resistance occur

Answer 4

Loop Diuretics

Question 5

This drug class is used to treat idiopathic hypercalciuria.

Answer 5

Thiazide/Thiazide-like Diuretics

Question 6

This drug class is used to treat diabetes insipidus. Has a paradoxical antidiuretic effect.

Answer 6

Thiazide/Thiazide-like diuretics

Question 7

This medication may crystallize when exposed to low temperatures and therefore a filter must be used when administered.

Answer 7

mannitol

Question 8

Indications: Hyperaldosteronism, HTN, reversing K loss, and HF

Answer 8

spironolactone

triamterene