CH. 3 Physiology & Histology Flashcards
The study of the structure & composition of skin tissue.
Skin Histology.
The study of living organisms.
Physiology.
Largest & one of the most important organs of the body.
Integumentary system (skin).
Where is the thinnest skin on the body?
Eyelids.
Where is the thickest skin on the body?
Palms & Soles of feet.
Appendages of the skin include…
Hair, nails, sweat, & oil glands.
Acid mantle is made up of…
sebum, lipids, sweat, & water.
Acid mantle has an average pH of…
5.5
Skin’s mechanism that protects from irritation & intercellular trans-epidermal water loss.
Barrier function.
Caused by evaporation on the skin surface.
TEWL
Substances that contribute to the barrier function of the epidermis.
Lipids.
The intercellular cement between epidermal cells is made up of…
Lipids.
The pigment in the eyes, hair, & skin that gives us some protection from UV rays emitted by the sun.
Melanin.
Most abundant in the fingertips, thus are designed to be one of the most sensitive parts of the body.
Sensory nerve fibers.
Average body temp is…
98.6
Accomplished by constriction of blood vessels & decreased blood flow. When the arrector pili muscles contract and cause “goose bumps”
Protection from cold.
Fat layers help insulate & warm the body.
Protection from heat.
Millions of sweat glands release heat from the body through…
Perspiration.
Excrete perspiration & detoxify the body by excreting excess water, salt, & unwanted chemicals through the pores.
Sudoriferous Glands. (aka sweat glands)
Sweat like sebum is part of the…
Acid Mantle.
Opening for the sweat glands…
Pores.
An oily substance that protects the surface of the skin & lubricates the skin & hair.
Sebum.
Soften the skin, & protect skin from outside elements
Sebaceous Glands.
Slows evaporation.
Sebum.
Penetration is determined by…
The size of the molecule.
Means “between” the cells.
Intercellular.
Means “across” or through the cells.
Transcellular.
What are the layers of the skin?
Epidermis & Dermis.
Outermost & thinnest layer of the skin.
Contains no blood vessels.
Has many nerve endingd & is composed of 5 layers.
Epidermis.
Composed of keratin, comprise 95% of the epidermis.
Contain both protein & lipids.
Keratinocyte.
The mother cells that divide in the basal layer forming new daughter cells.
Stem cells.
Composed of 5 layers called strata.
Epidermis layer.
Top outermost layer of the epidermis.
Thin yet waterproof, permeable regenerates itself, detoxifies the body, & responds to stimuli.
AKA the horny layer.
Stratum Corneum.
The shedding of keratinocytes between skin cells.
Desquamation.
Flat, scaly keratinized cells also called keratinocytes.
Squamous cells.
The average cell turnover rate for the skin cells of the epidermis is…
28 days.
The clear, transparent layer just under the skin surface.
It consists of small cells through which light can pass.
Also forms our unique fingerprints & footprints.
Stratum Lucidum.
Consists of cells that look like distinct granules & they are filled w/ keratin.
The production of keratin & intercellular lipids also take place here.
Stratum Granulosum.
Above the Stratum germinativum.
AKA the spiny layer.
Stratum Spinosum.
The protein bonds that create the junctions between the cells.
Desmosomes.
Protect the body from infections by identifying foreign material (antigens).
Langerhans cells.
Largest layer of the epidermis.
Stratum Spinosum.
Deepest layer in the epidermis.
In this layer, stem cells undergo continuous cell division.
Also contains melanocytes.
AKA basal cell layer.
Stratum Germinativum.
Cells that produce pigment granules.
Melanocytes.